Research Publications

Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity.

Giroux, NS; Ding, S; McClain, MT; Burke, TW; Petzold, E; Chung, HA; Palomino, GR; Wang, E; Xi, R; Bose, S; Rotstein, T; Nicholson, BP; Chen, T; Henao, R; Sempowski, GD; Denny, TN; Ko, ER; Ginsburg, GS; Kraft, BD; Tsalik, EL; Woods, CW; Shen, X. December 5, 2020

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Katsura, H; Sontake, V; Tata, A; Kobayashi, Y; Edwards, CE; Heaton, BE; Konkimalla, A; Asakura, T; Mikami, Y; Fritch, EJ; Lee, PJ; Heaton, NS; Boucher, RC; Randell, SH; Baric, RS; Tata, PR. December 3, 2020

A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism.

Enriquez-Hesles, E; Smith, DL; Maqani, N; Wierman, MB; Sutcliffe, MD; Fine, RD; Kalita, A; Santos, SM; Muehlbauer, MJ; Bain, JR; Janes, KA; Hartman, JL; Hirschey, MD; Smith, JS. December 2, 2020

Intimate partner violence and lower relationship quality are associated with faster biological aging.

Bourassa, KJ; Caspi, A; Harrington, H; Houts, R; Poulton, R; Ramrakha, S; Moffitt, TE. December 1, 2020

A polygenic score for age-at-first-birth predicts disinhibition.

Richmond-Rakerd, LS; Moffitt, TE; Arseneault, L; Belsky, DW; Connor, J; Corcoran, DL; Harrington, H; Houts, RM; Poulton, R; Prinz, JA; Ramrakha, S; Sugden, K; Wertz, J; Williams, BS; Caspi, A. December 1, 2020

Correction: Common-variant associations with fragile X syndrome.

Crowley, JJ; Szatkiewicz, J; Kähler, AK; Giusti-Rodriguez, P; Ancalade, N; Booker, JK; Carr, JL; Giamberardino, SN; Crawford, GE; Losh, M; Stockmeier, CA; Taylor, AK; Piven, J; Sullivan, PF. December 1, 2020

Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth.

Sakabe, NJ; Aneas, I; Knoblauch, N; Sobreira, DR; Clark, N; Paz, C; Horth, C; Ziffra, R; Kaur, H; Liu, X; Anderson, R; Morrison, J; Cheung, VC; Grotegut, C; Reddy, TE; Jacobsson, B; Hallman, M; Teramo, K; Murtha, A; Kessler, J; Grobman, W; Zhang, G; Muglia, LJ; Rana, S; Lynch, VJ; Crawford, GE; Ober, C; He, X; Nóbrega, MA. December 1, 2020

Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth.

Sakabe, NJ; Aneas, I; Knoblauch, N; Sobreira, DR; Clark, N; Paz, C; Horth, C; Ziffra, R; Kaur, H; Liu, X; Anderson, R; Morrison, J; Cheung, VC; Grotegut, C; Reddy, TE; Jacobsson, B; Hallman, M; Teramo, K; Murtha, A; Kessler, J; Grobman, W; Zhang, G; Muglia, LJ; Rana, S; Lynch, VJ; Crawford, GE; Ober, C; He, X; Nóbrega, MA. December 1, 2020

Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens.

Black, JB; McCutcheon, SR; Dube, S; Barrera, A; Klann, TS; Rice, GA; Adkar, SS; Soderling, SH; Reddy, TE; Gersbach, CA. December 1, 2020

Are changes in ADHD course reflected in differences in IQ and executive functioning from childhood to young adulthood?

Agnew-Blais, JC; Polanczyk, GV; Danese, A; Wertz, J; Moffitt, TE; Arseneault, L. December 1, 2020

Intimate partner violence and lower relationship quality are associated with faster biological aging.

Bourassa, KJ; Caspi, A; Harrington, H; Houts, R; Poulton, R; Ramrakha, S; Moffitt, TE. December 1, 2020

A polygenic score for age-at-first-birth predicts disinhibition.

Richmond-Rakerd, LS; Moffitt, TE; Arseneault, L; Belsky, DW; Connor, J; Corcoran, DL; Harrington, H; Houts, RM; Poulton, R; Prinz, JA; Ramrakha, S; Sugden, K; Wertz, J; Williams, BS; Caspi, A. December 1, 2020

Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens.

Black, JB; McCutcheon, SR; Dube, S; Barrera, A; Klann, TS; Rice, GA; Adkar, SS; Soderling, SH; Reddy, TE; Gersbach, CA. December 1, 2020

A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer.

Somarelli, JA; Roghani, RS; Moghaddam, AS; Thomas, BC; Rupprecht, G; Ware, KE; Altunel, E; Mantyh, JB; Kim, SY; McCall, SJ; Shen, X; Mantyh, CR; Hsu, DS. December 1, 2020

Coordinating and Assisting Research at the SARS-CoV-2/Microbiome Nexus.

Microbiome Centers Consortium COVID Committee,. December 1, 2020

Identifying the fitness consequences of sex in complex natural environments.

Rushworth, CA; Brandvain, Y; Mitchell-Olds, T. December 1, 2020

BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis.

Fan, H; Lu, J; Guo, Y; Li, D; Zhang, Z-M; Tsai, Y-H; Pi, W-C; Ahn, JH; Gong, W; Xiang, Y; Allison, DF; Geng, H; He, S; Diao, Y; Chen, W-Y; Strahl, BD; Cai, L; Song, J; Wang, GG. December 1, 2020

A cell non-autonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism.

Enriquez-Hesles, E; Smith, DL; Maqani, N; Wierman, MB; Sutcliffe, MD; Fine, RD; Kalita, A; Santos, SM; Muehlbauer, MJ; Bain, JR; Janes, KA; Hartman, JL; Hirschey, MD; Smith, JS. November 26, 2020