Research Publications

Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging.

Choi, J; Rakhilin, N; Gadamsetty, P; Joe, DJ; Tabrizian, T; Lipkin, SM; Huffman, DM; Shen, X; Nishimura, N. July 20, 2018

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Peyrot, WJ; Van der Auwera, S; Milaneschi, Y; Dolan, CV; Madden, PAF; Sullivan, PF; Strohmaier, J; Ripke, S; Rietschel, M; Nivard, MG; Mullins, N; Montgomery, GW; Henders, AK; Heat, AC; Fisher, HL; Dunn, EC; Byrne, EM; Air, TA; Wray, NR; Mattheisen, M; Trzaskowski, M; Abdellaoui, A; Adams, MJ; Agerbo, E; Air, TM; Andlauer, TFM; Bacanu, SA; Bækvad-Hansen, M; Beekman, ATF; Bigdeli, TB; Binder, EB; Blackwood, DHR; Bryois, J; Buttenschøn, HN; Bybjerg-Grauholm, J; Cai, N; Castelao, E; Christensen, JH; Clarke, TK; Coleman, JRI; Colodro-Conde, L; Couvy-Duchesne, B; Craddock, N; Crawford, GE; Davies, G; Deary, IJ; Degenhardt, F; Derks, EM; Direk, N; Eley, TC; Escott-Price, V; Farnush, ; Kiadeh, FH; Finucane, HK; Forstner, AJ; Frank, J; Gaspar, HA; Gill, M; Goes, FS; Gordon, SD; Grove, J; Hall, LS; Hansen, CS; Hansen, TF; Herms, S; Hicki, IB; Hoffmann, P; Homuth, G; Horn, C; Hottenga, JJ; Hougaard, DM; Ising, M; Jansen, R; Jorgenson, E; Knowles, JA; Kraft, J; Kretzschmar, WW; Krogh, J; Kutalik, Z. July 15, 2018

Dominance rank-associated immune gene expression is widespread, sex-specific, and a precursor to high social status in wild male baboons

Lea, A; Akinyi, M; Nyakundi, R; Mareri, P; Nyundo, F; Kariuki, T; Alberts, S; Archie, E; Tung, J. July 10, 2018

Genetic analysis of social-class mobility in five longitudinal studies.

Belsky, DW; Domingue, BW; Wedow, R; Arseneault, L; Boardman, JD; Caspi, A; Conley, D; Fletcher, JM; Freese, J; Herd, P; Moffitt, TE; Poulton, R; Sicinski, K; Wertz, J; Harris, KM. July 9, 2018

Genetic analysis of social-class mobility in five longitudinal studies.

Belsky, DW; Domingue, BW; Wedow, R; Arseneault, L; Boardman, JD; Caspi, A; Conley, D; Fletcher, JM; Freese, J; Herd, P; Moffitt, TE; Poulton, R; Sicinski, K; Wertz, J; Harris, KM. July 9, 2018

Genetic convergence of rare lymphomas.

Shingleton, JR; Dave, SS. July 1, 2018

Can a Framework Be Established for the Safe Use of Ketamine?

Freedman, R; Brown, AS; Cannon, TD; Druss, BG; Earls, FJ; Escobar, J; Hurd, YL; Lewis, DA; López-Jaramillo, C; Luby, J; Mayberg, HS; Moffitt, TE; Oquendo, M; Perlis, RH; Pine, DS; Rush, AJ; Tamminga, CA; Tohen, M; Vieta, E; Wisner, KL; Xin, Y. July 1, 2018

Human Gut Microbiota Predicts Susceptibility to Vibrio cholerae Infection.

Midani, FS; Weil, AA; Chowdhury, F; Begum, YA; Khan, AI; Debela, MD; Durand, HK; Reese, AT; Nimmagadda, SN; Silverman, JD; Ellis, CN; Ryan, ET; Calderwood, SB; Harris, JB; Qadri, F; David, LA; LaRocque, RC. July 1, 2018

Spatial Patterning from an Integrated Wnt/β-catenin and Notch/Delta Gene Circuit.

Mines, RC; Dohlman, A; Lim, S-X; Tung, K-L; Wang, E; Shen, X. July 1, 2018

Single-Cell Transcriptomics Reveals Heterogeneity and Drug Response of Human Colorectal Cancer Organoids.

Chen, K-Y; Srinivasan, T; Lin, C; Tung, K-L; Gao, Z; Hsu, DS; Lipkin, SM; Shen, X. July 1, 2018

Microbiota of Inflammatory Bowel Disease Models.

Gao, Z; Chen, K-Y; Mueller, O; Zhang, H; Rakhilin, N; Chen, J; Shen, X. July 1, 2018

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Savage, JE; Jansen, PR; Stringer, S; Watanabe, K; Bryois, J; de Leeuw, CA; Nagel, M; Awasthi, S; Barr, PB; Coleman, JRI; Grasby, KL; Hammerschlag, AR; Kaminski, JA; Karlsson, R; Krapohl, E; Lam, M; Nygaard, M; Reynolds, CA; Trampush, JW; Young, H; Zabaneh, D; Hägg, S; Hansell, NK; Karlsson, IK; Linnarsson, S; Montgomery, GW; Muñoz-Manchado, AB; Quinlan, EB; Schumann, G; Skene, NG; Webb, BT; White, T; Arking, DE; Avramopoulos, D; Bilder, RM; Bitsios, P; Burdick, KE; Cannon, TD; Chiba-Falek, O; Christoforou, A; Cirulli, ET; Congdon, E; Corvin, A; Davies, G; Deary, IJ; DeRosse, P; Dickinson, D; Djurovic, S; Donohoe, G; Conley, ED; Eriksson, JG; Espeseth, T; Freimer, NA; Giakoumaki, S; Giegling, I; Gill, M; Glahn, DC; Hariri, AR; Hatzimanolis, A; Keller, MC; Knowles, E; Koltai, D; Konte, B; Lahti, J; Le Hellard, S; Lencz, T; Liewald, DC; London, E; Lundervold, AJ; Malhotra, AK; Melle, I; Morris, D; Need, AC; Ollier, W; Palotie, A; Payton, A; Pendleton, N; Poldrack, RA; Räikkönen, K; Reinvang, I; Roussos, P; Rujescu, D; Sabb, FW; Scult, MA; Smeland, OB; Smyrnis, N; Starr, JM; Steen, VM; Stefanis, NC; Straub, RE; Sundet, K; Tiemeier, H; Voineskos, AN; Weinberger, DR; Widen, E; Yu, J; Abecasis, G; Andreassen, OA; Breen, G; Christiansen, L; Debrabant, B; Dick, DM; Heinz, A; Hjerling-Leffler, J; Ikram, MA; Kendler, KS; Martin, NG; Medland, SE; Pedersen, NL; Plomin, R; Polderman, TJC; Ripke, S; van der Sluis, S; Sullivan, PF; Vrieze, SI; Wright, MJ; Posthuma, D. July 1, 2018

Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition.

Peterson, BS; Campbell, JE; Ilkayeva, O; Grimsrud, PA; Hirschey, MD; Newgard, CB. July 1, 2018

Phenotypic characterization of murine models of cerebral cavernous malformations.

Zeineddine, HA; Girard, R; Saadat, L; Shen, L; Lightle, R; Moore, T; Cao, Y; Hobson, N; Shenkar, R; Avner, K; Chaudager, K; Koskimäki, J; Polster, SP; Fam, MD; Shi, C; Lopez-Ramirez, MA; Tang, AT; Gallione, C; Kahn, ML; Ginsberg, M; Marchuk, DA; Awad, IA. June 26, 2018

Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut.

Reese, AT; Cho, EH; Klitzman, B; Nichols, SP; Wisniewski, NA; Villa, MM; Durand, HK; Jiang, S; Midani, FS; Nimmagadda, SN; O'Connell, TM; Wright, JP; Deshusses, MA; David, LA. June 19, 2018

GlpR is a direct transcriptional repressor of fructose metabolic genes in Haloferax volcanii.

Martin, JH; Rawls, KS; Chan, JC; Hwang, S; Martinez-Pastor, M; McMillan, LJ; Prunetti, L; Schmid, AK; Maupin-Furlow, JA. June 18, 2018

Eleven Telomere, Epigenetic Clock, and Biomarker-Composite Quantifications of Biological Aging: Do They Measure the Same Thing?

Belsky, DW; Moffitt, TE; Cohen, AA; Corcoran, DL; Levine, ME; Prinz, JA; Schaefer, J; Sugden, K; Williams, B; Poulton, R; Caspi, A. June 1, 2018

Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood.

Marzi, SJ; Sugden, K; Arseneault, L; Belsky, DW; Burrage, J; Corcoran, DL; Danese, A; Fisher, HL; Hannon, E; Moffitt, TE; Odgers, CL; Pariante, C; Poulton, R; Williams, BS; Wong, CCY; Mill, J; Caspi, A. June 1, 2018