Research Publications

Methodologies for Following EMT In Vivo at Single Cell Resolution.

Massri, AJ; Schiebinger, GR; Berrio, A; Wang, L; Wray, GA; McClay, DR. January 1, 2021

In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy.

Kwon, JB; Ettyreddy, AR; Vankara, A; Bohning, JD; Devlin, G; Hauschka, SD; Asokan, A; Gersbach, CA. December 11, 2020

Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration

Chen, T; Oh, S; Gregory, S; Shen, X; Diehl, AM. November 19, 2020

Sirtuin 5 is Regulated by the SCF-Cyclin F Ubiquitin Ligase and is Involved in Cell Cycle Control.

Mills, CA; Wang, X; Bhatt, DP; Grimsrud, PA; Matson, JP; Lahiri, D; Burke, DJ; Cook, JG; Hirschey, MD; Emanuele, MJ. November 9, 2020

A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer.

Somarelli, JA; Salman Roghani, R; Sanjari Moghaddam, A; Thomas, BC; Rupprecht, G; Ware, KE; Altunel, E; Mantyh, JB; Kim, SY; McCall, SJ; Shen, X; Mantyh, CR; Hsu, DS. November 6, 2020

The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson's disease SNCA mutations.

Chen, V; Moncalvo, M; Tringali, D; Tagliafierro, L; Shriskanda, A; Ilich, E; Dong, W; Kantor, B; Chiba-Falek, O. November 4, 2020

In vivo optical metabolic imaging of long-chain fatty acid uptake in orthotopic models of triple negative breast cancer

Madonna, M; Duer, J; Lee, J; Williams, J; Avsaroglu, B; Zhu, C; Deutsch, R; Wang, R; Crouch, B; Hirschey, M; Goga, A; Ramanujam, N. November 2, 2020

BALO: a "mini lung" model to study cell-cell interactions.

Sontake, V; Tata, PR. November 2, 2020

DNA mismatches reveal conformational penalties in protein-DNA recognition.

Afek, A; Shi, H; Rangadurai, A; Sahay, H; Senitzki, A; Xhani, S; Fang, M; Salinas, R; Mielko, Z; Pufall, MA; Poon, GMK; Haran, TE; Schumacher, MA; Al-Hashimi, HM; Gordân, R. November 1, 2020

Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.

Cholan, PM; Han, A; Woodie, BR; Watchon, M; Kurz, AR; Laird, AS; Britton, WJ; Ye, L; Holmes, ZC; McCann, JR; David, LA; Rawls, JF; Oehlers, SH. November 1, 2020

Novel Murine Models of Cerebral Cavernous Malformations.

Detter, MR; Shenkar, R; Benavides, CR; Neilson, CA; Moore, T; Lightle, R; Hobson, N; Shen, L; Cao, Y; Girard, R; Zhang, D; Griffin, E; Gallione, CJ; Awad, IA; Marchuk, DA. November 1, 2020

Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.

Cholan, PM; Han, A; Woodie, BR; Watchon, M; Kurz, AR; Laird, AS; Britton, WJ; Ye, L; Holmes, ZC; McCann, JR; David, LA; Rawls, JF; Oehlers, SH. November 1, 2020

Molecular Clocks without Rocks: New Solutions for Old Problems.

Tiley, GP; Poelstra, JW; Dos Reis, M; Yang, Z; Yoder, AD. November 1, 2020

Is cardiovascular fitness associated with structural brain integrity in midlife? Evidence from a population-representative birth cohort study.

d'Arbeloff, T; Cooke, M; Knodt, AR; Sison, M; Melzer, TR; Ireland, D; Poulton, R; Ramrakha, S; Moffitt, TE; Caspi, A; Hariri, AR. October 21, 2020

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Katsura, H; Sontake, V; Tata, A; Kobayashi, Y; Edwards, CE; Heaton, BE; Konkimalla, A; Asakura, T; Mikami, Y; Fritch, EJ; Lee, PJ; Heaton, NS; Boucher, RC; Randell, SH; Baric, RS; Tata, PR. October 21, 2020

Transcriptional and proteomic insights into the host response in fatal COVID-19 cases.

Wu, M; Chen, Y; Xia, H; Wang, C; Tan, CY; Cai, X; Liu, Y; Ji, F; Xiong, P; Liu, R; Guan, Y; Duan, Y; Kuang, D; Xu, S; Cai, H; Xia, Q; Yang, D; Wang, M-W; Chiu, IM; Cheng, C; Ahern, PP; Liu, L; Wang, G; Surana, NK; Xia, T; Kasper, DL. October 20, 2020

Single cell transcriptomics of mouse kidney transplants reveals a myeloid cell pathway for transplant rejection.

Dangi, A; Natesh, NR; Husain, I; Ji, Z; Barisoni, L; Kwun, J; Shen, X; Thorp, EB; Luo, X. October 15, 2020