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Molecular Genetics of Vascular Malformations
A post-doctoral position is available to investigate the role of somatic mutation in vascular malformation syndromes. This newly funded study will investigate vascular malformations that have been proposed to follow a two-hit mutation mechanism, as previously described by our laboratory for Cerebral Cavernous Malformations (CCM). See Akers et al., 2009, Human Molecular Genetics 18:919-930, PMC26402099, and McDonald et al., 2014. Human Molecular Genetics 23:4357-70, PMC4103679 for our published studies on CCM.
The ideal applicant will have previous experience with library construction for next-generation DNA sequencing and with analysis of the sequence data.
Please submit a cover letter outlining your professional interests, your CV, pdfs of up to three of your published papers, and the names and email addresses of three references to Douglas.Marchuk@duke.edu