Research Publications

An intravital window to image the colon in real time.

Rakhilin, N; Garrett, A; Eom, C-Y; Chavez, KR; Small, DM; Daniel, AR; Kaelberer, MM; Mejooli, MA; Huang, Q; Ding, S; Kirsch, DG; Bohórquez, DV; Nishimura, N; Barth, BB; Shen, X. December 11, 2019

Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort.

Elliott, ML; Belsky, DW; Knodt, AR; Ireland, D; Melzer, TR; Poulton, R; Ramrakha, S; Caspi, A; Moffitt, TE; Hariri, AR. December 10, 2019

Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort.

Elliott, ML; Belsky, DW; Knodt, AR; Ireland, D; Melzer, TR; Poulton, R; Ramrakha, S; Caspi, A; Moffitt, TE; Hariri, AR. December 10, 2019

Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease.

Assiri, MA; Ali, HR; Marentette, JO; Yun, Y; Liu, J; Hirschey, MD; Saba, LM; Harris, PS; Fritz, KS. December 10, 2019

Replicability of structural brain alterations associated with general psychopathology: evidence from a population-representative birth cohort.

Romer, AL; Knodt, AR; Sison, ML; Ireland, D; Houts, R; Ramrakha, S; Poulton, R; Keenan, R; Melzer, TR; Moffitt, TE; Caspi, A; Hariri, AR. December 3, 2019

Replicability of structural brain alterations associated with general psychopathology: evidence from a population-representative birth cohort.

Romer, AL; Knodt, AR; Sison, ML; Ireland, D; Houts, R; Ramrakha, S; Poulton, R; Keenan, R; Melzer, TR; Moffitt, TE; Caspi, A; Hariri, AR. December 3, 2019

High fat diet induces microbiota-dependent silencing of enteroendocrine cells.

Ye, L; Mueller, O; Bagwell, J; Bagnat, M; Liddle, RA; Rawls, JF. December 3, 2019

Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate.

Lopatkin, AJ; Stokes, JM; Zheng, EJ; Yang, JH; Takahashi, MK; You, L; Collins, JJ. December 1, 2019

Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imaging.

Walzer, KA; Fradin, H; Emerson, LY; Corcoran, DL; Chi, J-T. December 1, 2019

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells.

Pickar-Oliver, A; Black, JB; Lewis, MM; Mutchnick, KJ; Klann, TS; Gilcrest, KA; Sitton, MJ; Nelson, CE; Barrera, A; Bartelt, LC; Reddy, TE; Beisel, CL; Barrangou, R; Gersbach, CA. December 1, 2019

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells.

Pickar-Oliver, A; Black, JB; Lewis, MM; Mutchnick, KJ; Klann, TS; Gilcrest, KA; Sitton, MJ; Nelson, CE; Barrera, A; Bartelt, LC; Reddy, TE; Beisel, CL; Barrangou, R; Gersbach, CA. December 1, 2019

Quality of Life in Children With Sturge-Weber Syndrome.

Harmon, KA; Day, AM; Hammill, AM; Pinto, AL; McCulloch, CE; Comi, AM; National Institutes of Health Rare Disease Clinical Research Consortium (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group,. December 1, 2019

Rare-variant collapsing analyses for complex traits: guidelines and applications.

Povysil, G; Petrovski, S; Hostyk, J; Aggarwal, V; Allen, AS; Goldstein, DB. December 1, 2019

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.

Tang, AT; Sullivan, KR; Hong, CC; Goddard, LM; Mahadevan, A; Ren, A; Pardo, H; Peiper, A; Griffin, E; Tanes, C; Mattei, LM; Yang, J; Li, L; Mericko-Ishizuka, P; Shen, L; Hobson, N; Girard, R; Lightle, R; Moore, T; Shenkar, R; Polster, SP; Roedel, CJ; Li, N; Zhu, Q; Whitehead, KJ; Zheng, X; Akers, A; Morrison, L; Kim, H; Bittinger, K; Lengner, CJ; Schwaninger, M; Velcich, A; Augenlicht, L; Abdelilah-Seyfried, S; Min, W; Marchuk, DA; Awad, IA; Kahn, ML. November 27, 2019

Persistence of a novel regeneration-associated transitional cell state in pulmonary fibrosis

Kobayashi, Y; Tata, A; Konkimalla, A; Katsura, H; Lee, R; Ou, J; Banovich, N; Kropski, J; Tata, PR. November 25, 2019

Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.

Huang, J; Chen, M; Xu, ES; Luo, L; Ma, Y; Huang, W; Floyd, W; Klann, TS; Kim, SY; Gersbach, CA; Cardona, DM; Kirsch, DG. November 20, 2019

Circular ecDNA promotes accessible chromatin and high oncogene expression.

Wu, S; Turner, KM; Nguyen, N; Raviram, R; Erb, M; Santini, J; Luebeck, J; Rajkumar, U; Diao, Y; Li, B; Zhang, W; Jameson, N; Corces, MR; Granja, JM; Chen, X; Coruh, C; Abnousi, A; Houston, J; Ye, Z; Hu, R; Yu, M; Kim, H; Law, JA; Verhaak, RGW; Hu, M; Furnari, FB; Chang, HY; Ren, B; Bafna, V; Mischel, PS. November 20, 2019

Whole Exome and Transcriptome Sequencing in 1042 Cases Reveals Distinct Clinically Relevant Genetic Subgroups of Follicular Lymphoma.

Li, X; Kositsky, R; Reddy, A; Love, C; Naresh, K; Koff, JL; Nystrand, I; Leppä, S; Pasanen, A; Karjalainen-Lindsberg, M-L; Dunkel, J; Kovanen, P; Qin, Q; Bhagat, G; Leeman-Neill, RJ; Goswami, RS; Wildeman, S; Delabie, J; Burack, R; Evans, AG; Amador, C; Yuan, J; Qureishi, HN; Li, S; Xu, J; Yin, CC; Gang, AO; Norgaard, PH; Pedersen, MØ; Chan, JY; Cheah, DMZ; Ong, SY; Cheng, CL; Lee, L; Paulua, F; Ondrejka, SL; Hsi, ED; Czader, M; Wang, L; Landis, A; Churnetski, MC; Jaye, DL; Flowers, CR; McCall, CM; Neff, J; McKinney, MS; Fedoriw, Y; Powers, E; Montgomery, ND; Bogusz, AM; Stafford Hintz, A; Kovach, AE; Reddy, N; Thompson Arildsen, MA; Mason, EF; Juskevicius, R; Choi, W; Au-Yeung, R; Tse, E; Sarno, V; Chadburn, A; Lopez, R; Chapman, JR; Behdad, A; Goldschmidt, N; Goodlad, J; Burton, C; Pillai, R; Louissaint, A; Soliman, DS; Panea, R; Dave, T; Xiong, B; Smith, E; Dave, S. November 13, 2019

Are changes in ADHD course reflected in differences in IQ and executive functioning from childhood to young adulthood?

Agnew-Blais, JC; Polanczyk, GV; Danese, A; Wertz, J; Moffitt, TE; Arseneault, L. November 13, 2019

Association of Adverse Experiences and Exposure to Violence in Childhood and Adolescence With Inflammatory Burden in Young People.

Rasmussen, LJH; Moffitt, TE; Arseneault, L; Danese, A; Eugen-Olsen, J; Fisher, HL; Harrington, H; Houts, R; Matthews, T; Sugden, K; Williams, B; Caspi, A. November 4, 2019