Research Publications

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells.

Pickar-Oliver, A; Black, JB; Lewis, MM; Mutchnick, KJ; Klann, TS; Gilcrest, KA; Sitton, MJ; Nelson, CE; Barrera, A; Bartelt, LC; Reddy, TE; Beisel, CL; Barrangou, R; Gersbach, CA. December 1, 2019

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells.

Pickar-Oliver, A; Black, JB; Lewis, MM; Mutchnick, KJ; Klann, TS; Gilcrest, KA; Sitton, MJ; Nelson, CE; Barrera, A; Bartelt, LC; Reddy, TE; Beisel, CL; Barrangou, R; Gersbach, CA. December 1, 2019

Quality of Life in Children With Sturge-Weber Syndrome.

Harmon, KA; Day, AM; Hammill, AM; Pinto, AL; McCulloch, CE; Comi, AM; National Institutes of Health Rare Disease Clinical Research Consortium (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group,. December 1, 2019

Rare-variant collapsing analyses for complex traits: guidelines and applications.

Povysil, G; Petrovski, S; Hostyk, J; Aggarwal, V; Allen, AS; Goldstein, DB. December 1, 2019

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.

Tang, AT; Sullivan, KR; Hong, CC; Goddard, LM; Mahadevan, A; Ren, A; Pardo, H; Peiper, A; Griffin, E; Tanes, C; Mattei, LM; Yang, J; Li, L; Mericko-Ishizuka, P; Shen, L; Hobson, N; Girard, R; Lightle, R; Moore, T; Shenkar, R; Polster, SP; Roedel, CJ; Li, N; Zhu, Q; Whitehead, KJ; Zheng, X; Akers, A; Morrison, L; Kim, H; Bittinger, K; Lengner, CJ; Schwaninger, M; Velcich, A; Augenlicht, L; Abdelilah-Seyfried, S; Min, W; Marchuk, DA; Awad, IA; Kahn, ML. November 27, 2019

Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.

Huang, J; Chen, M; Xu, ES; Luo, L; Ma, Y; Huang, W; Floyd, W; Klann, TS; Kim, SY; Gersbach, CA; Cardona, DM; Kirsch, DG. November 20, 2019

Whole Exome and Transcriptome Sequencing in 1042 Cases Reveals Distinct Clinically Relevant Genetic Subgroups of Follicular Lymphoma.

Li, X; Kositsky, R; Reddy, A; Love, C; Naresh, K; Koff, JL; Nystrand, I; Leppä, S; Pasanen, A; Karjalainen-Lindsberg, M-L; Dunkel, J; Kovanen, P; Qin, Q; Bhagat, G; Leeman-Neill, RJ; Goswami, RS; Wildeman, S; Delabie, J; Burack, R; Evans, AG; Amador, C; Yuan, J; Qureishi, HN; Li, S; Xu, J; Yin, CC; Gang, AO; Norgaard, PH; Pedersen, MØ; Chan, JY; Cheah, DMZ; Ong, SY; Cheng, CL; Lee, L; Paulua, F; Ondrejka, SL; Hsi, ED; Czader, M; Wang, L; Landis, A; Churnetski, MC; Jaye, DL; Flowers, CR; McCall, CM; Neff, J; McKinney, MS; Fedoriw, Y; Powers, E; Montgomery, ND; Bogusz, AM; Stafford Hintz, A; Kovach, AE; Reddy, N; Thompson Arildsen, MA; Mason, EF; Juskevicius, R; Choi, W; Au-Yeung, R; Tse, E; Sarno, V; Chadburn, A; Lopez, R; Chapman, JR; Behdad, A; Goldschmidt, N; Goodlad, J; Burton, C; Pillai, R; Louissaint, A; Soliman, DS; Panea, R; Dave, T; Xiong, B; Smith, E; Dave, S. November 13, 2019

Are changes in ADHD course reflected in differences in IQ and executive functioning from childhood to young adulthood?

Agnew-Blais, JC; Polanczyk, GV; Danese, A; Wertz, J; Moffitt, TE; Arseneault, L. November 13, 2019

The whole-genome landscape of Burkitt lymphoma subtypes.

Panea, RI; Love, CL; Shingleton, JR; Reddy, A; Bailey, JA; Moormann, AM; Otieno, JA; Ong'echa, JM; Oduor, CI; Schroeder, KMS; Masalu, N; Chao, NJ; Agajanian, M; Major, MB; Fedoriw, Y; Richards, KL; Rymkiewicz, G; Miles, RR; Alobeid, B; Bhagat, G; Flowers, CR; Ondrejka, SL; Hsi, ED; Choi, WWL; Au-Yeung, RKH; Hartmann, W; Lenz, G; Meyerson, H; Lin, Y-Y; Zhuang, Y; Luftig, MA; Waldrop, A; Dave, T; Thakkar, D; Sahay, H; Li, G; Palus, BC; Seshadri, V; Kim, SY; Gascoyne, RD; Levy, S; Mukhopadyay, M; Dunson, DB; Dave, SS. November 7, 2019

Somatic Mutations in Vascular Malformations of Hereditary Hemorrhagic Telangiectasia Result in Bi-allelic Loss of ENG or ACVRL1.

Snellings, DA; Gallione, CJ; Clark, DS; Vozoris, NT; Faughnan, ME; Marchuk, DA. November 7, 2019

Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation.

Dall'Agnese, A; Caputo, L; Nicoletti, C; di Iulio, J; Schmitt, A; Gatto, S; Diao, Y; Ye, Z; Forcato, M; Perera, R; Bicciato, S; Telenti, A; Ren, B; Puri, PL. November 7, 2019

Association of Adverse Experiences and Exposure to Violence in Childhood and Adolescence With Inflammatory Burden in Young People.

Rasmussen, LJH; Moffitt, TE; Arseneault, L; Danese, A; Eugen-Olsen, J; Fisher, HL; Harrington, H; Houts, R; Matthews, T; Sugden, K; Williams, B; Caspi, A. November 4, 2019

Association of Adverse Experiences and Exposure to Violence in Childhood and Adolescence With Inflammatory Burden in Young People.

Rasmussen, LJH; Moffitt, TE; Arseneault, L; Danese, A; Eugen-Olsen, J; Fisher, HL; Harrington, H; Houts, R; Matthews, T; Sugden, K; Williams, B; Caspi, A. November 4, 2019

Emerging strategies for engineering microbial communities.

Tsoi, R; Dai, Z; You, L. November 1, 2019

The propensity for aggressive behavior and lifetime incarceration risk: A test for gene-environment interaction (G × E) using whole-genome data

Barnes, JC; Liu, H; Motz, RT; Tanksley, PT; Kail, R; Beckley, AL; Belsky, DW; Domingue, BW; Moffitt, TE; Pratt, TC; Wertz, J. November 1, 2019

An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.

Evans, BC; Fletcher, RB; Kilchrist, KV; Dailing, EA; Mukalel, AJ; Colazo, JM; Oliver, M; Cheung-Flynn, J; Brophy, CM; Tierney, JW; Isenberg, JS; Hankenson, KD; Ghimire, K; Lander, C; Gersbach, CA; Duvall, CL. November 1, 2019

Novel Neuroprotective Loci Modulating Ischemic Stroke Volume in Wild-Derived Inbred Mouse Strains.

Lee, HK; Widmayer, SJ; Huang, M-N; Aylor, DL; Marchuk, DA. November 1, 2019

Predictors of mortality in patients with hereditary hemorrhagic telangiectasia

Faughnan, ME; Nelson, J; Kim, H; Pawlikowska, L; Marchuk, DA; Lawton, MT. November 1, 2019

HHT telangiectases contain biallelic mutations in ENG/ACVRL1

Snellings, DA; Gallione, CJ; Clark, DS; Vozoris, NT; Faughnan, ME; Marchuk, DA. November 1, 2019

Common genetic variants associated with immune or inflammatory traits and disease severity phenotypes in hereditary hemorrhagic telangiectasia

Pawlikowska, L; Nelson, J; McCulloch, CE; Lawton, MT; Marchuk, DA; Kim, H; Faughnan, ME. November 1, 2019