Research Publications

Behavioral and Social Research to Accelerate the Geroscience Translation Agenda.

Moffitt, TE. November 1, 2020

DNA methylation signatures of a broad spectrum of aggressive behavior: a meta-analysis of epigenome-wide studies across the lifespan

van Dongen, J; Hagenbeek, FA; Suderman, M; Roetman, P; Sugden, K; Chiocchetti, AG; Ismail, K; Mulder, RH; Hafferty, J; Adams, MJ; Walker, RM; Morris, SW; Lahti, J; Kupers, LK; Escaramis, G; Alemany, S; Bonder, MJ; Meijer, M; Ip, HF; Jansen, R; Baselmans, BML; Parmar, P; Lowry, E; Streit, F; Sirignano, L; Send, T; Frank, J; Jylhava, J; Wang, Y; Mishra, PP; Colins, OF; Corcoran, D; Poulton, R; Mill, J; Hannon, EJ; Arseneault, L; Korhonen, T; Vuoksimaa, E; Felix, J; Bakermans-Kranenburg, M; Campbell, A; Czamara, D; Binder, E; Corpeleijn, E; Ramon Gonzalez, J; Grazuleviciene, R; Gutzkow, KB; Evandt, J; Vafeiadi, M; Klein, M; van der Meer, D; Ligthart, L; Kluft, C; Davies, GE; Hakulinen, C; Keltikangas-Jarvinen, L; Franke, B; Freitag, CM; Konrad, K; Hervas, A; Fernandez-Rivas, A; Vetro, A; Raitakari, O; Lehtimaki, T; Vermeiren, R; Strandberg, T; Raikkonen, K; Snieder, H; Witt, SH; Deuschle, M; Pedersen, NL; Hagg, S; Sunyer, J; Franke, L; Kaprio, J; Ollikainen, M; Moffitt, TE; Tiemeier, H; van Ijzendoorn, MH; Relton, C; Vrijheid, M; Sebert, S; Jarvelin, M-R; Caspi, A; Evans, KL; McIntosh, AM; Bartels, M; Boomsma, D. November 1, 2020

Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife.

Reuben, A; Elliott, ML; Abraham, WC; Broadbent, J; Houts, RM; Ireland, D; Knodt, AR; Poulton, R; Ramrakha, S; Hariri, AR; Caspi, A; Moffitt, TE. November 1, 2020

Delinquency abstainers in adolescence and educational and labor market outcomes in midlife: A population-based 25-year longitudinal study.

Pedersen, W; Hart, RK; Moffitt, TE; von Soest, T. November 1, 2020

DNA mismatches reveal conformational penalties in protein-DNA recognition.

Afek, A; Shi, H; Rangadurai, A; Sahay, H; Senitzki, A; Xhani, S; Fang, M; Salinas, R; Mielko, Z; Pufall, MA; Poon, GMK; Haran, TE; Schumacher, MA; Al-Hashimi, HM; Gordân, R. November 1, 2020

Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.

Cholan, PM; Han, A; Woodie, BR; Watchon, M; Kurz, AR; Laird, AS; Britton, WJ; Ye, L; Holmes, ZC; McCann, JR; David, LA; Rawls, JF; Oehlers, SH. November 1, 2020

Novel Murine Models of Cerebral Cavernous Malformations.

Detter, MR; Shenkar, R; Benavides, CR; Neilson, CA; Moore, T; Lightle, R; Hobson, N; Shen, L; Cao, Y; Girard, R; Zhang, D; Griffin, E; Gallione, CJ; Awad, IA; Marchuk, DA. November 1, 2020

Individualizing pharmacogenomic test results in the context of the microbiome.

Haga, SB. November 1, 2020

Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.

Cholan, PM; Han, A; Woodie, BR; Watchon, M; Kurz, AR; Laird, AS; Britton, WJ; Ye, L; Holmes, ZC; McCann, JR; David, LA; Rawls, JF; Oehlers, SH. November 1, 2020

Molecular Clocks without Rocks: New Solutions for Old Problems.

Tiley, GP; Poelstra, JW; Dos Reis, M; Yang, Z; Yoder, AD. November 1, 2020

A Bayesian non-parametric mixed-effects model of microbial growth curves.

Tonner, PD; Darnell, CL; Bushell, FML; Lund, PA; Schmid, AK; Schmidler, SC. October 26, 2020

Is cardiovascular fitness associated with structural brain integrity in midlife? Evidence from a population-representative birth cohort study.

d'Arbeloff, T; Cooke, M; Knodt, AR; Sison, M; Melzer, TR; Ireland, D; Poulton, R; Ramrakha, S; Moffitt, TE; Caspi, A; Hariri, AR. October 21, 2020

Is cardiovascular fitness associated with structural brain integrity in midlife? Evidence from a population-representative birth cohort study.

d'Arbeloff, T; Cooke, M; Knodt, AR; Sison, M; Melzer, TR; Ireland, D; Poulton, R; Ramrakha, S; Moffitt, TE; Caspi, A; Hariri, AR. October 21, 2020

A longitudinal twin study of victimization and loneliness from childhood to young adulthood.

Matthews, T; Caspi, A; Danese, A; Fisher, HL; Moffitt, TE; Arseneault, L. October 13, 2020

A longitudinal twin study of victimization and loneliness from childhood to young adulthood.

Matthews, T; Caspi, A; Danese, A; Fisher, HL; Moffitt, TE; Arseneault, L. October 13, 2020

A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre.

Cheung, CY; Xu, D; Cheng, C-Y; Sabanayagam, C; Tham, Y-C; Yu, M; Rim, TH; Chai, CY; Gopinath, B; Mitchell, P; Poulton, R; Moffitt, TE; Caspi, A; Yam, JC; Tham, CC; Jonas, JB; Wang, YX; Song, SJ; Burrell, LM; Farouque, O; Li, LJ; Tan, G; Ting, DSW; Hsu, W; Lee, ML; Wong, TY. October 12, 2020

A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre.

Cheung, CY; Xu, D; Cheng, C-Y; Sabanayagam, C; Tham, Y-C; Yu, M; Rim, TH; Chai, CY; Gopinath, B; Mitchell, P; Poulton, R; Moffitt, TE; Caspi, A; Yam, JC; Tham, CC; Jonas, JB; Wang, YX; Song, SJ; Burrell, LM; Farouque, O; Li, LJ; Tan, G; Ting, DSW; Hsu, W; Lee, ML; Wong, TY. October 12, 2020

Good problems to have? Policy and societal implications of a disease-modifying therapy for presymptomatic late-onset Alzheimer's disease.

Angrist, M; Yang, A; Kantor, B; Chiba-Falek, O. October 12, 2020

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.

Hong, CC; Tang, AT; Detter, MR; Choi, JP; Wang, R; Yang, X; Guerrero, AA; Wittig, CF; Hobson, N; Girard, R; Lightle, R; Moore, T; Shenkar, R; Polster, SP; Goddard, LM; Ren, AA; Leu, NA; Sterling, S; Yang, J; Li, L; Chen, M; Mericko-Ishizuka, P; Dow, LE; Watanabe, H; Schwaninger, M; Min, W; Marchuk, DA; Zheng, X; Awad, IA; Kahn, ML. October 5, 2020

Borderline Symptoms at Age 12 Signal Risk for Poor Outcomes During the Transition to Adulthood: Findings From a Genetically Sensitive Longitudinal Cohort Study.

Wertz, J; Caspi, A; Ambler, A; Arseneault, L; Belsky, DW; Danese, A; Fisher, HL; Matthews, T; Richmond-Rakerd, LS; Moffitt, TE. October 1, 2020