Research Publications

An imprecise path to precision medicine.

Shen, X. January 1, 2020

Robocop: Multivariate state space model integrating epigenomic accessibility data to elucidate genome-wide chromatin occupancy

Mitra, S; Zhong, J; MacAlpine, DM; Hartemink, AJ. January 1, 2020

Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases.

Rittiner, JE; Moncalvo, M; Chiba-Falek, O; Kantor, B. January 1, 2020

The emergence of microbiome centres.

Martiny, JBH; Whiteson, KL; Bohannan, BJM; David, LA; Hynson, NA; McFall-Ngai, M; Rawls, JF; Schmidt, TM; Abdo, Z; Blaser, MJ; Bordenstein, S; Bréchot, C; Bull, CT; Dorrestein, P; Eisen, JA; Garcia-Pichel, F; Gilbert, J; Hofmockel, KS; Holtz, ML; Knight, R; Mark Welch, DB; McDonald, D; Methé, B; Mouncey, NJ; Mueller, NT; Pfister, CA; Proctor, L; Sachs, JL. January 1, 2020

Chromosomal Evolution and Apomixis in the Cruciferous Tribe Boechereae.

Mandáková, T; Hloušková, P; Windham, MD; Mitchell-Olds, T; Ashby, K; Price, B; Carman, J; Lysak, MA. January 1, 2020

Erythromyeloid progenitors give rise to a population of osteoclasts that contribute to bone homeostasis and repair.

Yahara, Y; Barrientos, T; Tang, YJ; Puviindran, V; Nadesan, P; Zhang, H; Gibson, JR; Gregory, SG; Diao, Y; Xiang, Y; Qadri, YJ; Souma, T; Shinohara, ML; Alman, BA. January 1, 2020

Conservation genomic analysis reveals ancient introgression and declining levels of genetic diversity in Madagascar's hibernating dwarf lemurs.

Williams, RC; Blanco, MB; Poelstra, JW; Hunnicutt, KE; Comeault, AA; Yoder, AD. January 1, 2020

Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals.

Hunnicutt, KE; Tiley, GP; Williams, RC; Larsen, PA; Blanco, MB; Rasoloarison, RM; Campbell, CR; Zhu, K; Weisrock, DW; Matsunami, H; Yoder, AD. January 1, 2020

Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells and protects against liver fibrosis

Du, K; Oh, SH; Sun, T; Yang, W-H; Chi, J-TA; Diehl, AM. December 23, 2019

SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.

Naiman, S; Huynh, FK; Gil, R; Glick, Y; Shahar, Y; Touitou, N; Nahum, L; Avivi, MY; Roichman, A; Kanfi, Y; Gertler, AA; Doniger, T; Ilkayeva, OR; Abramovich, I; Yaron, O; Lerrer, B; Gottlieb, E; Harris, RA; Gerber, D; Hirschey, MD; Cohen, HY. December 17, 2019

Universal antibiotic tolerance arising from antibiotic-triggered accumulation of pyocyanin in Pseudomonas aeruginosa.

Zhu, K; Chen, S; Sysoeva, TA; You, L. December 16, 2019

An intravital window to image the colon in real time.

Rakhilin, N; Garrett, A; Eom, C-Y; Chavez, KR; Small, DM; Daniel, AR; Kaelberer, MM; Mejooli, MA; Huang, Q; Ding, S; Kirsch, DG; Bohórquez, DV; Nishimura, N; Barth, BB; Shen, X. December 11, 2019

Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort.

Elliott, ML; Belsky, DW; Knodt, AR; Ireland, D; Melzer, TR; Poulton, R; Ramrakha, S; Caspi, A; Moffitt, TE; Hariri, AR. December 10, 2019

Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort.

Elliott, ML; Belsky, DW; Knodt, AR; Ireland, D; Melzer, TR; Poulton, R; Ramrakha, S; Caspi, A; Moffitt, TE; Hariri, AR. December 10, 2019

Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease.

Assiri, MA; Ali, HR; Marentette, JO; Yun, Y; Liu, J; Hirschey, MD; Saba, LM; Harris, PS; Fritz, KS. December 10, 2019

Replicability of structural brain alterations associated with general psychopathology: evidence from a population-representative birth cohort.

Romer, AL; Knodt, AR; Sison, ML; Ireland, D; Houts, R; Ramrakha, S; Poulton, R; Keenan, R; Melzer, TR; Moffitt, TE; Caspi, A; Hariri, AR. December 3, 2019

Replicability of structural brain alterations associated with general psychopathology: evidence from a population-representative birth cohort.

Romer, AL; Knodt, AR; Sison, ML; Ireland, D; Houts, R; Ramrakha, S; Poulton, R; Keenan, R; Melzer, TR; Moffitt, TE; Caspi, A; Hariri, AR. December 3, 2019

High fat diet induces microbiota-dependent silencing of enteroendocrine cells.

Ye, L; Mueller, O; Bagwell, J; Bagnat, M; Liddle, RA; Rawls, JF. December 3, 2019

Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate.

Lopatkin, AJ; Stokes, JM; Zheng, EJ; Yang, JH; Takahashi, MK; You, L; Collins, JJ. December 1, 2019

Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imaging.

Walzer, KA; Fradin, H; Emerson, LY; Corcoran, DL; Chi, J-T. December 1, 2019