Research Publications

Pervasively Thinner Neocortex as a Transdiagnostic Feature of General Psychopathology.

Romer, AL; Elliott, ML; Knodt, AR; Sison, ML; Ireland, D; Houts, R; Ramrakha, S; Poulton, R; Keenan, R; Melzer, TR; Moffitt, TE; Caspi, A; Hariri, AR. February 1, 2021

Identifying Adolescents at Risk for Depression: A Prediction Score Performance in Cohorts Based in 3 Different Continents.

Rocha, TB-M; Fisher, HL; Caye, A; Anselmi, L; Arseneault, L; Barros, FC; Caspi, A; Danese, A; Gonçalves, H; Harrington, HL; Houts, R; Menezes, AMB; Moffitt, TE; Mondelli, V; Poulton, R; Rohde, LA; Wehrmeister, F; Kieling, C. February 1, 2021

Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models.

Li, W; Shenkar, R; Detter, MR; Moore, T; Benavides, C; Lightle, R; Girard, R; Hobson, N; Cao, Y; Li, Y; Griffin, E; Gallione, C; Zabramski, JM; Ginsberg, MH; Marchuk, DA; Awad, IA. February 1, 2021

Casual Genetic Variants in Stillbirth

Stanley, KE; Giordano, J; Thorsten, V; Buchovecky, C; Thomas, A; Ganapathi, M; Liao, J; Dharmadhikari, AV; Revah-Politi, A; Ernst, M; Lippa, N; Holmes, H; Povysil, G; Hostyk, J; Parker, CB; Goldenberg, R; Saade, GR; Dudley, DJ; Pinar, H; Hogue, C; Reddy, UM; Silver, RM; Aggarwal, V; Allen, AS; Wapner, RJ; Goldstein, DB. February 1, 2021

Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome.

Hwang, H; Szucs, MJ; Ding, LJ; Allen, A; Ren, X; Haensgen, H; Gao, F; Rhim, H; Andrade, A; Pan, JQ; Carr, SA; Ahmad, R; Xu, W. February 1, 2021

Cryptic Patterns of Speciation in Cryptic Primates: Microendemic Mouse Lemurs and the Multispecies Coalescent.

Poelstra, JW; Salmona, J; Tiley, GP; Schüßler, D; Blanco, MB; Andriambeloson, JB; Bouchez, O; Campbell, CR; Etter, PD; Hohenlohe, PA; Hunnicutt, KE; Iribar, A; Johnson, EA; Kappeler, PM; Larsen, PA; Manzi, S; Ralison, JM; Randrianambinina, B; Rasoloarison, RM; Rasolofoson, DW; Stahlke, AR; Weisrock, DW; Williams, RC; Chikhi, L; Louis, EE; Radespiel, U; Yoder, AD. February 1, 2021

The hard clam genome reveals massive expansion and diversification of inhibitors of apoptosis in Bivalvia.

Song, H; Guo, X; Sun, L; Wang, Q; Han, F; Wang, H; Wray, GA; Davidson, P; Wang, Q; Hu, Z; Zhou, C; Yu, Z; Yang, M; Feng, J; Shi, P; Zhou, Y; Zhang, L; Zhang, T. January 25, 2021

Sirtuin 5 Is Regulated by the SCFCyclin F Ubiquitin Ligase and Is Involved in Cell Cycle Control.

Mills, CA; Wang, X; Bhatt, DP; Grimsrud, PA; Matson, JP; Lahiri, D; Burke, DJ; Cook, JG; Hirschey, MD; Emanuele, MJ. January 25, 2021

Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone.

Gonzalez-Hunt, CP; Luz, AL; Ryde, IT; Turner, EA; Ilkayeva, OR; Bhatt, DP; Hirschey, MD; Meyer, JN. January 15, 2021

Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity.

Sarvestani, SK; Signs, S; Hu, B; Yeu, Y; Feng, H; Ni, Y; Hill, DR; Fisher, RC; Ferrandon, S; DeHaan, RK; Stiene, J; Cruise, M; Hwang, TH; Shen, X; Spence, JR; Huang, EH. January 11, 2021

Selfing is the safest sex for <i>Caenorhabditis tropicalis</i>.

Noble, LM; Yuen, J; Stevens, L; Moya, N; Persaud, R; Moscatelli, M; Jackson, JL; Zhang, G; Chitrakar, R; Baugh, LR; Braendle, C; Andersen, EC; Seidel, HS; Rockman, MV. January 11, 2021

Polygenic Risk and the Course of Attention-Deficit/Hyperactivity Disorder From Childhood to Young Adulthood: Findings From a Nationally Representative Cohort.

Agnew-Blais, JC; Belsky, DW; Caspi, A; Danese, A; Moffitt, TE; Polanczyk, GV; Sugden, K; Wertz, J; Williams, BS; Lewis, CM; Arseneault, L. January 10, 2021

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.

van Dongen, J; Hagenbeek, FA; Suderman, M; Roetman, PJ; Sugden, K; Chiocchetti, AG; Ismail, K; Mulder, RH; Hafferty, JD; Adams, MJ; Walker, RM; Morris, SW; Lahti, J; Küpers, LK; Escaramis, G; Alemany, S; Jan Bonder, M; Meijer, M; Ip, HF; Jansen, R; Baselmans, BML; Parmar, P; Lowry, E; Streit, F; Sirignano, L; Send, TS; Frank, J; Jylhävä, J; Wang, Y; Mishra, PP; Colins, OF; Corcoran, DL; Poulton, R; Mill, J; Hannon, E; Arseneault, L; Korhonen, T; Vuoksimaa, E; Felix, JF; Bakermans-Kranenburg, MJ; Campbell, A; Czamara, D; Binder, E; Corpeleijn, E; Gonzalez, JR; Grazuleviciene, R; Gutzkow, KB; Evandt, J; Vafeiadi, M; Klein, M; van der Meer, D; Ligthart, L; BIOS Consortium, ; Kluft, C; Davies, GE; Hakulinen, C; Keltikangas-Järvinen, L; Franke, B; Freitag, CM; Konrad, K; Hervas, A; Fernández-Rivas, A; Vetro, A; Raitakari, O; Lehtimäki, T; Vermeiren, R; Strandberg, T; Räikkönen, K; Snieder, H; Witt, SH; Deuschle, M; Pedersen, NL; Hägg, S; Sunyer, J; Franke, L; Kaprio, J; Ollikainen, M; Moffitt, TE; Tiemeier, H; van IJzendoorn, MH; Relton, C; Vrijheid, M; Sebert, S; Jarvelin, M-R; Caspi, A; Evans, KL; McIntosh, AM; Bartels, M; Boomsma, DI. January 8, 2021

Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.

Demange, PA; Malanchini, M; Mallard, TT; Biroli, P; Cox, SR; Grotzinger, AD; Tucker-Drob, EM; Abdellaoui, A; Arseneault, L; van Bergen, E; Boomsma, DI; Caspi, A; Corcoran, DL; Domingue, BW; Harris, KM; Ip, HF; Mitchell, C; Moffitt, TE; Poulton, R; Prinz, JA; Sugden, K; Wertz, J; Williams, BS; de Zeeuw, EL; Belsky, DW; Harden, KP; Nivard, MG. January 7, 2021

Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences.

Murphy, J; Shevlin, M; Arseneault, L; Bentall, R; Caspi, A; Danese, A; Hyland, P; Moffitt, TE; Fisher, HL. January 6, 2021

Predictors of mortality in patients with hereditary hemorrhagic telangiectasia.

Thompson, KP; Nelson, J; Kim, H; Pawlikowska, L; Marchuk, DA; Lawton, MT; Faughnan, ME; Brain Vascular Malformation Consortium HHT Investigator Group,. January 6, 2021

In Vivo Optical Metabolic Imaging of Long-Chain Fatty Acid Uptake in Orthotopic Models of Triple-Negative Breast Cancer.

Madonna, MC; Duer, JE; Lee, JV; Williams, J; Avsaroglu, B; Zhu, C; Deutsch, R; Wang, R; Crouch, BT; Hirschey, MD; Goga, A; Ramanujam, N. January 5, 2021

Longitudinal Associations of Mental Disorders With Physical Diseases and Mortality Among 2.3 Million New Zealand Citizens.

Richmond-Rakerd, LS; D'Souza, S; Milne, BJ; Caspi, A; Moffitt, TE. January 4, 2021