Research Publications

Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy.

Nelson, CE; Wu, Y; Gemberling, MP; Oliver, ML; Waller, MA; Bohning, JD; Robinson-Hamm, JN; Bulaklak, K; Castellanos Rivera, RM; Collier, JH; Asokan, A; Gersbach, CA. March 1, 2019

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.

Shenkar, R; Peiper, A; Pardo, H; Moore, T; Lightle, R; Girard, R; Hobson, N; Polster, SP; Koskimäki, J; Zhang, D; Lyne, SB; Cao, Y; Chaudagar, K; Saadat, L; Gallione, C; Pytel, P; Liao, JK; Marchuk, D; Awad, IA. March 1, 2019

Phenotypic characterization of murine models of cerebral cavernous malformations.

Zeineddine, HA; Girard, R; Saadat, L; Shen, L; Lightle, R; Moore, T; Cao, Y; Hobson, N; Shenkar, R; Avner, K; Chaudager, K; Koskimäki, J; Polster, SP; Fam, MD; Shi, C; Lopez-Ramirez, MA; Tang, AT; Gallione, C; Kahn, ML; Ginsberg, M; Marchuk, DA; Awad, IA. March 1, 2019

Effect of Sociodemographic Factors on Uptake of a Patient-Facing Information Technology Family Health History Risk Assessment Platform.

Wu, RR; Myers, RA; Buchanan, AH; Dimmock, D; Fulda, KG; Haller, IV; Haga, SB; Harry, ML; McCarty, C; Neuner, J; Rakhra-Burris, T; Sperber, N; Voils, CI; Ginsburg, GS; Orlando, LA. March 1, 2019

Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization.

Murdoch, CC; Espenschied, ST; Matty, MA; Mueller, O; Tobin, DM; Rawls, JF. March 1, 2019

Evolution of DNA Methylation in Papio Baboons.

Vilgalys, TP; Rogers, J; Jolly, CJ; Mukherjee, S; Tung, J. March 1, 2019

Establishing a generalized polyepigenetic biomarker for tobacco smoking.

Sugden, K; Hannon, EJ; Arseneault, L; Belsky, DW; Broadbent, JM; Corcoran, DL; Hancox, RJ; Houts, RM; Moffitt, TE; Poulton, R; Prinz, JA; Thomson, WM; Williams, BS; Wong, CCY; Mill, J; Caspi, A. February 15, 2019

Establishing a generalized polyepigenetic biomarker for tobacco smoking.

Sugden, K; Hannon, EJ; Arseneault, L; Belsky, DW; Broadbent, JM; Corcoran, DL; Hancox, RJ; Houts, RM; Moffitt, TE; Poulton, R; Prinz, JA; Thomson, WM; Williams, BS; Wong, CCY; Mill, J; Caspi, A. February 15, 2019

Climate and Land Cover Analysis Suggest No Strong Ecological Barriers to Gene Flow in a Natural Baboon Hybrid Zone

Wango, TL; Musiega, D; Mundia, CN; Altmann, J; Alberts, SC; Tung, J. February 15, 2019

Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome.

Halyabar, O; Chang, MH; Schoettler, ML; Schwartz, MA; Baris, EH; Benson, LA; Biggs, CM; Gorman, M; Lehmann, L; Lo, MS; Nigrovic, PA; Platt, CD; Priebe, GP; Rowe, J; Sundel, RP; Surana, NK; Weinacht, KG; Mann, A; Yuen, JC; Meleedy-Rey, P; Starmer, A; Banerjee, T; Dedeoglu, F; Degar, BA; Hazen, MM; Henderson, LA. February 14, 2019

Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.

Koskimäki, J; Girard, R; Li, Y; Saadat, L; Zeineddine, HA; Lightle, R; Moore, T; Lyne, S; Avner, K; Shenkar, R; Cao, Y; Shi, C; Polster, SP; Zhang, D; Carrión-Penagos, J; Romanos, S; Fonseca, G; Lopez-Ramirez, MA; Chapman, EM; Popiel, E; Tang, AT; Akers, A; Faber, P; Andrade, J; Ginsberg, M; Derry, WB; Kahn, ML; Marchuk, DA; Awad, IA. February 7, 2019

Improved Pathogenic Variant Localization via a Hierarchical Model of Sub-regional Intolerance.

Hayeck, TJ; Stong, N; Wolock, CJ; Copeland, B; Kamalakaran, S; Goldstein, DB; Allen, AS. February 7, 2019

Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.

Fisher-Wellman, KH; Draper, JA; Davidson, MT; Williams, AS; Narowski, TM; Slentz, DH; Ilkayeva, OR; Stevens, RD; Wagner, GR; Najjar, R; Hirschey, MD; Thompson, JW; Olson, DP; Kelly, DP; Koves, TR; Grimsrud, PA; Muoio, DM. February 5, 2019

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis.

Hartwig, FP; Davies, NM; Horta, BL; Ahluwalia, TS; Bisgaard, H; Bønnelykke, K; Caspi, A; Moffitt, TE; Poulton, R; Sajjad, A; Tiemeier, HW; Dalmau-Bueno, A; Guxens, M; Bustamante, M; Santa-Marina, L; Parker, N; Paus, T; Pausova, Z; Lauritzen, L; Schnurr, TM; Michaelsen, KF; Hansen, T; Oddy, W; Pennell, CE; Warrington, NM; Davey Smith, G; Victora, CG. February 1, 2019

Cumulative childhood risk is associated with a new measure of chronic inflammation in adulthood.

Rasmussen, LJH; Moffitt, TE; Eugen-Olsen, J; Belsky, DW; Danese, A; Harrington, H; Houts, RM; Poulton, R; Sugden, K; Williams, B; Caspi, A. February 1, 2019

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.

Coleman, JRI; Bryois, J; Gaspar, HA; Jansen, PR; Savage, JE; Skene, N; Plomin, R; Muñoz-Manchado, AB; Linnarsson, S; Crawford, G; Hjerling-Leffler, J; Sullivan, PF; Posthuma, D; Breen, G. February 1, 2019

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis.

Hartwig, FP; Davies, NM; Horta, BL; Ahluwalia, TS; Bisgaard, H; Bønnelykke, K; Caspi, A; Moffitt, TE; Poulton, R; Sajjad, A; Tiemeier, HW; Dalmau-Bueno, A; Guxens, M; Bustamante, M; Santa-Marina, L; Parker, N; Paus, T; Pausova, Z; Lauritzen, L; Schnurr, TM; Michaelsen, KF; Hansen, T; Oddy, W; Pennell, CE; Warrington, NM; Davey Smith, G; Victora, CG. February 1, 2019

Exploration of NO2 and PM2.5 air pollution and mental health problems using high-resolution data in London-based children from a UK longitudinal cohort study.

Roberts, S; Arseneault, L; Barratt, B; Beevers, S; Danese, A; Odgers, CL; Moffitt, TE; Reuben, A; Kelly, FJ; Fisher, HL. February 1, 2019

Cumulative childhood risk is associated with a new measure of chronic inflammation in adulthood.

Rasmussen, LJH; Moffitt, TE; Eugen-Olsen, J; Belsky, DW; Danese, A; Harrington, H; Houts, RM; Poulton, R; Sugden, K; Williams, B; Caspi, A. February 1, 2019