Research Publications

Cumulative childhood risk is associated with a new measure of chronic inflammation in adulthood.

Rasmussen, LJH; Moffitt, TE; Eugen-Olsen, J; Belsky, DW; Danese, A; Harrington, H; Houts, RM; Poulton, R; Sugden, K; Williams, B; Caspi, A. February 1, 2019

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.

Coleman, JRI; Bryois, J; Gaspar, HA; Jansen, PR; Savage, JE; Skene, N; Plomin, R; Muñoz-Manchado, AB; Linnarsson, S; Crawford, G; Hjerling-Leffler, J; Sullivan, PF; Posthuma, D; Breen, G. February 1, 2019

Cumulative childhood risk is associated with a new measure of chronic inflammation in adulthood.

Rasmussen, LJH; Moffitt, TE; Eugen-Olsen, J; Belsky, DW; Danese, A; Harrington, H; Houts, RM; Poulton, R; Sugden, K; Williams, B; Caspi, A. February 1, 2019

Multiplication of the SNCA locus exacerbates neuronal nuclear aging.

Tagliafierro, L; Zamora, ME; Chiba-Falek, O. February 1, 2019

General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks.

Elliott, ML; Knodt, AR; Cooke, M; Kim, MJ; Melzer, TR; Keenan, R; Ireland, D; Ramrakha, S; Poulton, R; Caspi, A; Moffitt, TE; Hariri, AR. January 29, 2019

General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks.

Elliott, ML; Knodt, AR; Cooke, M; Kim, MJ; Melzer, TR; Keenan, R; Ireland, D; Ramrakha, S; Poulton, R; Caspi, A; Moffitt, TE; Hariri, AR. January 29, 2019

Megaphages infect Prevotella and variants are widespread in gut microbiomes.

Devoto, AE; Santini, JM; Olm, MR; Anantharaman, K; Munk, P; Tung, J; Archie, EA; Turnbaugh, PJ; Seed, KD; Blekhman, R; Aarestrup, FM; Thomas, BC; Banfield, JF. January 28, 2019

Association of Childhood Lead Exposure With Adult Personality Traits and Lifelong Mental Health.

Reuben, A; Schaefer, JD; Moffitt, TE; Broadbent, J; Harrington, H; Houts, RM; Ramrakha, S; Poulton, R; Caspi, A. January 23, 2019

Association of Childhood Lead Exposure With Adult Personality Traits and Lifelong Mental Health.

Reuben, A; Schaefer, JD; Moffitt, TE; Broadbent, J; Harrington, H; Houts, RM; Ramrakha, S; Poulton, R; Caspi, A. January 23, 2019

SENP3-mediated host defense response contains HBV replication and restores protein synthesis.

Xi, R; Kadur Lakshminarasimha Murthy, P; Tung, K-L; Guy, CD; Wan, J; Li, F; Wang, Z; Li, X; Varanko, A; Rakhilin, N; Xin, Y; Liu, B; Qian, S-B; Su, L; Han, Y; Shen, X. January 14, 2019

Adolescents Who Self-Harm and Commit Violent Crime: Testing Early-Life Predictors of Dual Harm in a Longitudinal Cohort Study.

Richmond-Rakerd, LS; Caspi, A; Arseneault, L; Baldwin, JR; Danese, A; Houts, RM; Matthews, T; Wertz, J; Moffitt, TE. January 4, 2019

Lonely young adults in modern Britain: findings from an epidemiological cohort study.

Matthews, T; Danese, A; Caspi, A; Fisher, HL; Goldman-Mellor, S; Kepa, A; Moffitt, TE; Odgers, CL; Arseneault, L. January 1, 2019

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Barbu, MC; Zeng, Y; Shen, X; Cox, SR; Clarke, TK; Gibson, J; Adams, MJ; Johnstone, M; Haley, CS; Lawrie, SM; Deary, IJ; Wray, NR; Ripke, S; Mattheisen, M; Trzaskowski, M; Byrne, EM; Abdellaoui, A; Agerbo, E; Air, TM; Andlauer, TFM; Bacanu, SA; Bækvad-Hansen, M; Beekman, ATF; Bigdeli, TB; Binder, EB; Blackwood, DHR; Bryois, J; Buttenschøn, HN; Bybjerg-Grauholm, J; Cai, N; Castelao, E; Christensen, JH; Coleman, JRI; Colodro-Conde, L; Couvy-Duchesne, B; Craddock, N; Crawford, GE; Davies, G; Degenhardt, F; Derks, EM; Direk, N; Dolan, CV; Dunn, EC; Eley, TC; Escott-Price, V; Hassan Kiadeh, FF; Finucane, HK; Forstner, AJ; Frank, J; Gaspar, HA; Gill, M; Goes, FS; Gordon, SD; Grove, J; Hall, LS; Hansen, CS; Hansen, TF; Herms, S; Hickie, IB; Hoffmann, P; Homuth, G; Horn, C; Hottenga, JJ; Hougaard, DM; Ising, M; Jansen, R; Jorgenson, E; Knowles, JA; Kohane, IS; Kraft, J; Kretzschmar, WW; Krogh, J; Kutalik, Z; Li, Y; Lind, PA; MacIntyre, DJ; MacKinnon, DF; Maier, RM; Maier, W; Marchini, J; Mbarek, H; McGrath, P; McGuffin, P; Medland, SE; Mehta, D; Middeldorp, CM; Mihailov, E; Milaneschi, Y; Milani, L; Mondimore, FM; Montgomery, GW; Mostafavi, S; Mullins, N; Nauck, M; Ng, B; Nivard, MG. January 1, 2019

Identifying gene expression from single cells to single genes

Oulhen, N; Foster, S; Wray, G; Wessel, G. January 1, 2019

Lonely young adults in modern Britain: findings from an epidemiological cohort study.

Matthews, T; Danese, A; Caspi, A; Fisher, HL; Goldman-Mellor, S; Kepa, A; Moffitt, TE; Odgers, CL; Arseneault, L. January 1, 2019

Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing.

Adkar, SS; Wu, C-L; Willard, VP; Dicks, A; Ettyreddy, A; Steward, N; Bhutani, N; Gersbach, CA; Guilak, F. January 1, 2019

Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes.

Chen, L-F; Lin, YT; Gallegos, DA; Hazlett, MF; Gómez-Schiavon, M; Yang, MG; Kalmeta, B; Zhou, AS; Holtzman, L; Gersbach, CA; Grandl, J; Buchler, NE; West, AE. January 1, 2019

Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo.

Xu, Y; Huang, L; Kirschman, JL; Vanover, DA; Tiwari, PM; Santangelo, PJ; Shen, X; Russell, DG. January 1, 2019

Hypothesis: Presymptomatic treatment of Sturge-Weber Syndrome With Aspirin and Antiepileptic Drugs May Delay Seizure Onset.

Day, AM; Hammill, AM; Juhász, C; Pinto, AL; Roach, ES; McCulloch, CE; Comi, AM; National Institutes of Health Sponsor: Rare Diseases Clinical Research Network (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group,. January 1, 2019