TBP-bound mismatched vs Watson-Crick DNA
GCB News

Transcription Factors May Inadvertently Lock in DNA Mistakes

Binding to mismatched DNA takes less energy; may explain how regulatory mutations get locked in

Center News

Xiling Shen addresses the crowd at the inaugural Precision Medicine Conference
November 6, 2019

Inaugural Precision Medicine Conference Held at Duke

Hosted by the Woo Center for Big Data and Precision Medicine, directed by GCB faculty member Xiling Shen, the new conference brought together leaders in data-driven approaches to improving health.
October 31, 2019

Programming Cell Behavior

With work spanning gene circuits, antibiotic resistance and the mathematical modeling of cellular networks, GCB faculty Lingchong You explores how to best to harness microbes for medical purposes.
Credit: Pixabay.
October 11, 2019

DNA Metabarcoding Useful for Analyzing Human Diet

Lawrence David launches new study demonstrating that DNA metabarcoding provides a promising new method for tracking human plant intake, suggesting that similar approaches could be used to characterize the animal and fungal components of human diets.
The Duke Center for Advanced Genomic Technologies aims to investigate and re-engineer the inner workings of cellular gene regulation machinery and networks
September 30, 2019

New Duke Center Takes Aim at the Dark Genome

The Center for Advanced Genomic Technologies, directed by GCB faculty member Charlie Gersbach, will use homegrown tools and techniques to discover potential therapies for human diseases from autism to cancer to schizophrenia.