GCB News

On Thursday, October 11, Doug Marchuk will host an all-day meeting with seven other project leaders from the Leducq Foundation Network, ATTRACT: Arterial flow as an attractor for endothelial cell migration. Marchuk is serving as the North American coordinator on this grant. During the meeting, each project leader will present their current research for the project.

Highlights to the current issue include:

New NSF grant links four Duke engineers to explore how mechanical changes to genetic material affects gene expression, cancer development.

Being low on the pecking order often means poorer health — but why?

Bass Connections released their 2018 Annual Report, which features the two Bass Connections projects that GCB co-led in the 2017-2018 academic year: Blue Devil Resistome and Enabling Precision Health and Medicine.

By 2020, the Parkinson’s Foundation estimates that nearly one million people will be living with Parkinson’s disease (PD) in the U.S. That’s more than the number of people diagnosed with multiple sclerosis, muscular dystrophy and Lou Gehrig’s disease combined. Researchers at Duke are taking action.

Thousands of professionals are using discoveries in genomics, genetics and medicine to revolutionize the world. Students interested in careers in genome sciences and medicine need a strong foundation of core genome sciences, technology and interdisciplinary training.

Greg Wray and Susanne Haga are co-teaching a new undergraduate course this fall called Current Technologies in Genomics and Precision Medicine  (BIO325/MGM325). The course aims to provide a comprehensive overview of genome science technologies, analytical tools, clinical applications, and related issues. Students will gain exposure to a range of technologies currently used in research and some in clinical practice, as well as the tools to interrogate the large data-sets generated by these technologies.

Here are summaries of a selection of the papers published by GCB faculty in July and August 2018:

TRANSCRIPTION FACTORS AND GENE EXPRESSION

The Reddy lab, in collaboration with Charlie Gersbach and Greg Crawford, investigated what controls interactions between glucocorticoid receptor binding sites and their target genes. Read more

The Duke Center for Applied Genomics and Precision Medicine wrapped up the inaugural year of the Snyderman Scholars Applied Genomics & Precision Medicine Summer Program on July 25. The goal of the program is to enable students to initiate or continue research in applied genomics or precision medicine over the summer.