GCB News

Float Like a Butterfly, Sting Like an Algorithm

Bruce Donald and colleagues developed RESISTOR, an algorithm that uses protein structure-based computational design to predict how mutations in an enzyme will affect a drug’s efficacy. This technology could provide drug designers with insights to design better, more durable, proactive drugs.

Microbial Job Stability

How functions in microbial communities remain constant despite varying compositions

Microbial communities, whether those found in the human gut, marine waters, seaweed, or wild bromeliads, can vary drastically, both in their species numbers and in composition. But despite the variations, certain functions in these microbial communities stay stable, and now researchers at Duke are understanding why.