GCB Hosts Open House at the Chesterfield

Chesterfield building, interior view of the atrium skylights
GCB News

GCB Hosts Open House at the Chesterfield

On Friday, February 2, GCB hosted an open house at the newly remodeled Chesterfield Building in downtown Durham to celebrate the new laboratory spaces for two of its core facilities: The Sequencing & Genomic Technologies Shared Resource (SGT) and the Proteomics & Metabolomics Share Resource (DPMSR).

The open house allowed the Duke research community an opportunity to tour the new state-of-the-art lab spaces for the two core facilities and learn more about not only the cores themselves, but also the research the cores have helped others at Duke conduct. Representatives from Agilent Technologies, Illumina, Waters Corporation and Thermo Fisher Scientific educated guests about their equipment and capabilities.

People gathered in the atrium of the Chesterfield buildingRaphael Valdivia, Vice Dean of Basic Science, gave the opening remarks and highlighted the importance of Duke’s presence at the Chesterfield because it will help allow world-class science to flourish at Duke. SGT and DPMSR’s expansion at the Chesterfield will help Duke create more space for both planned and unplanned collisions and interactions both within the other Duke labs and outside industries located in the Chesterfield building.

Both cores offer a variety of services to help PIs and research groups plan a wide variety of investigations, including sample preparation, data production, quality control, and analysis and dissemination. Four Duke faculty gave brief presentations to describe how their research has been positively impacted by SGT and DPMSR.

Professor and Co-Vice Chair for Molecular Genetics and Microbiology, Sue Jinks-Robertson utilized PacBio’s Single Molecule Real-Time (SMRT) technology for targeted gene sequencing to investigate the effects of transcription on stability of the underlying DNA. Steve Haase, associate professor of biology, utilized RNA sequencing technology available through SGT to sequence whole blood samples from patients infected with malaria to help investigate clock control of malarial diseases. With the help of DPMSR, clinical investigator Susanna Naggie was able to use proteomics to predict the sustained viral response in high-risk patients with HIV/HCV co-infection and discover proteomic biomarkers in HIV and HCV to help improve patient diagnosis and treatment plans using a combined pharmacogenomics/proteomic approach. In investigating inhibitory synapses in the brain, professor of cell biology and neurobiology, Scott Soderling collaborated with the DPMSR for their label free quantitative mass spectrometry services to discover novel proteins enriched in inhibitory synapses in vivo.

The cores also presented core vouchers to 12 lab groups. Over 40 applications had been received.

Voucher Winners:

DPMSR:

Vadim Arshavsky
Helena Rubinstein Foundation Professor of Ophthalmology
Pharmacology and Cancer Biology
Duke Eye Center

Christina Barkauskas
Assistant Professor of Medicine – Pulmonary, Allergy and Critical Care
Duke’s Regeneration NEXT Initiative

Ann Marie Pendergast                                
Anthony R. Means Cancer Biology Professor      
Pharmacology and Cancer Biology          
Duke Cancer Institute

Scott Soderling & Tyler Bradshaw            
Professor of Cell Biology
Associate Prof. of Neurobiology                                                               
Duke Institute for Brain Sciences & Duke Cancer Institute                                             

SGT:

Robert Fitak
Postdoc in the Johnsen lab
Biology department

David Murdoch
Associate Professor of Medicine
Duke University School of Medicine

Shelley Hwang
Professor of Surgery and Radiology, Vice Chair of Research in the Dept. of Surgery
Duke University School of Medicine

Alejandro Antonia
Graduate student in the Ko lab
Molecular Genetics and Microbiology

Elizabeth Hunsaker
Graduate student in the Franz lab
Chemistry department

Ryan Baugh
Associate Professor of Biology
Biology Department

Ornit Chiba-Falek
Associate Professor of Neurology
Duke University School of Medicine

Abdull Massri
Biology Department

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