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Claire Engstrom, a Student Researcher Working to Treat Duchenne’s Muscular Dystrophy by Optimizing CRISPR-cas9

Meet Claire Engstrom, a Senior from Pasadena California. Claire is a Biology major who works in the Gersbach Lab at Duke.

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Figure Caption: CRISPR-based activation of gene networks implicated in human stem cells becoming neuronal cells led to the generation of cells with neuronal shapes and markers (left) and enhanced function and electrophysiological properties, including producing more action potentials more frequently (right).

GCB News

It’s time to grow up

Stem cells have the potential to turn into any cell type, which makes them an incredibly powerful tool for disease modeling and...

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GCB News

GCB Welcomes New Members

This fall, GCB welcomed two new members: Anne Yoder, Ph.D., and Purushothama Rao Tata, Ph.D.

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December 1, 2020

Research Roundup: November 2020

Here are summaries of a selection of the papers published by GCB faculty in November 2020:

November 23, 2020

Incorporating Genomics into Lymphoma Classification Can Improve Care

By Lynne Lederman, Ph.D. - Targeted Oncology

November 18, 2020

Childhood Lead Exposure Leads to Structural Changes in Middle-aged Brains

Study participants had lead exposures typical for the 1970s

By Karl Leif Bates

The list of equations required to model three plasmids being swapped in one bacterial species using the old method (left) versus the new, simplified model’s equations (right)

November 10, 2020

Researchers Discover Bacterial DNA’s Recipe for Success

A single criterion predicts whether a genetic package such as antibiotic resistance will thrive in a given environment

By Ken Kingery

November 2, 2020

Multidisciplinary University Research Initiative tackles synthetic biology

Lingchong You and Ashutosh Chilkoti, are collaborators on a five-year, $7.5 million MURI award.

November 2, 2020

Research Roundup: October 2020

Here are summaries of a selection of the papers published by GCB faculty in October 2020

collage of protein constructions of SARS-CoV-2

October 23, 2020

Spring Seminar on Computational Biology focuses on SARS-Cov-2 and COVID-19

Bruce Donald, James B. Duke Distinguished Professor of Computer Science, will offer a seminar in the spring focused on COVID-19, SARS-CoV-2 and therapeutic design.

October 23, 2020

GCB helps spin out success

In FY20, 17 new start-up companies formed at Duke, according to Duke’s Office of Licensing and Ventures (OLV).

TBP-bound mismatched vs Watson-Crick DNA

October 21, 2020

Transcription Factors May Inadvertently Lock in DNA Mistakes

Binding to mismatched DNA takes less energy; may explain how regulatory mutations get locked in

SARS-CoV-2, the coronavirus that causes COVID-19, appears to have evolved silent changes to its RNA code that gave it a biological edge over previous strains. Credit: Felipe Esquivel Reed

October 16, 2020

PINPOINTING THE 'SILENT' MUTATIONS THAT GAVE THE CORONAVIRUS AN EVOLUTIONARY EDGE

RNA folding may help explain how the coronavirus became so hard to stop after it spilled over from wildlife to humans.

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Research Roundup: December 2020

Center News

Featured Posts

Claire Engstrom, a Student Researcher Working to Treat Duchenne’s Muscular Dystrophy by Optimizing CRISPR-cas9

It’s time to grow up

GCB Welcomes New Members

Research Roundup: November 2020

Incorporating Genomics into Lymphoma Classification Can Improve Care

Childhood Lead Exposure Leads to Structural Changes in Middle-aged Brains

Researchers Discover Bacterial DNA’s Recipe for Success

Multidisciplinary University Research Initiative tackles synthetic biology

Research Roundup: October 2020

Spring Seminar on Computational Biology focuses on SARS-Cov-2 and COVID-19

GCB helps spin out success

Transcription Factors May Inadvertently Lock in DNA Mistakes

PINPOINTING THE 'SILENT' MUTATIONS THAT GAVE THE CORONAVIRUS AN EVOLUTIONARY EDGE

Duke Microbiome Center Seminar

Duke Research Week 2021

CBB Seminar: Integrated approaches to define cells and cell states in health and disease