The Ruth K. Broad Foundation Seminar Series on Neurobiology and Disease

The Ruth K. Broad Foundation Seminar Series on Neurobiology and Disease

June 4, 2019 12:00pm to 1:00pm
Jennifer Lippincott-Schwartz
National Institutes of Health

Location: Bryan Research 103

The lab's goal is to understand the interplay of membrane-bound organelles, cytoskeletal structure, and metabolism as it relates to the organization and function of neurons, and the cells they interact with. On a small scale, we are interested in mapping out the spatial organization, stoichiometry, and dynamics of proteins as they interact with each other and with different parts of the cell. On a larger scale, we are trying to decipher how complex cellular behaviors arise, including cell crawling, polarization, cell-cell contact, cytokinesis, cell fate determination, viral budding, and intercellular transfer. To study these problems, we rely heavily on microscopy - including super-resolution imaging techniques and cutting edge fluorescence-based technologies - as well as biochemistry, in vitro reconstitution, and mathematical modeling.