Matthew Hirschey

Matt Hirschey, Ph.D.
(919) 479-2315
104775, Room 50-201
Durham, NC 27701

Matthew Hirschey

Associate Professor in Medicine

The overall objective of the Hirschey Lab is to better understand metabolism and mitochondrial function, which is important for human health and several human diseases. Their research focuses on metabolism, with a particular interest in how cells use metabolites and chemical modifications to protein in order to regulate metabolism. The lab studies the regulation of this process by a family of enzymes called sirtuins, and how they maintain energy homeostasis. Their work has important implications for diabetes and obesity, cardiovascular disease, cancer, inborn errors, and the aging process itself.

Recent Publications

Mills, CA; Trub, AG; Hirschey, MD
January 1, 2019
Peterson, BS; Campbell, JE; Ilkayeva, O; Grimsrud, PA; Hirschey, MD; Newgard, CB
July 1, 2018
Hu, Y; Semova, I; Sun, X; Kang, H; Chahar, S; Hollenberg, AN; Masson, D; Hirschey, MD; Miao, J; Biddinger, SB
February 1, 2018