Sandeep Dave, MD, MS

Sandeep Dave
919.681.1922
2163 CIEMAS 101 Science Drive, Box 33821 Durham, NC 27708

Sandeep Dave, MD, MS

Associate Professor, Division of Hematologic Malignancies & Cellular Therapy, Department of Medicine
High-throughput technologies will transform the way we diagnose and treat malignancies.

Leukemias and lymphomas are malignancies that arise from immune cells. The majority of these malignancies arise from B cells, a type of immune cell. Leukemias and lymphomas derived from B cells affect over 100,000 Americans every year. The majority of those patients will succumb to their disease. Dr. Dave's research is focused on the application of high-throughput technologies including microarrays and massively parallel sequencing to improve the diagnosis and treatment of leukemias and lymphomas.

Active efforts in the laboratory and clinic include:

  1. Integrating genomic technologies with clinical trials to define molecular subgroups of patients who are most likely to respond to therapy.
  2. Exploring the role of microRNA in the differentiation of immune cells and their role in leukemias and lymphomas.
  3. Application of high throughput sequencing to identify means of gene regulation in normal and malignant cells.
  4. Exploiting high throughput genomic and proteomic technologies to develop new prognostic and diagnostic markers in leukemias and lymphomas.

Sandeep Dave completed an M.S. in Biomedical Engineering and was in the combined M.D./M.B.A. program at Northwestern University Medical School/Kellogg Graduate School of Management. After medical school, he completed a residency in internal medicine at Northwestern and a clinical and post-doctoral fellowship in hematology-oncology at the National Institutes of Health.

He was won many awards for his research and teaching including the prestigious Fellows Award in Research Excellence at the National Institutes of Health. His work is focused on the application of high throughput technologies to identify new therapeutic targets, as well as markers of diagnosis and prognosis in patients with leukemias and lymphomas.

Research Interests

Media portrayals of genomics
microRNA
Gene Regulation
Gene Expression Profiling
Leukemia and Lymphoma

Recent Publications

Reddy, A; Zhang, J; Davis, NS; Moffitt, AB; Love, CL; Waldrop, A; Leppa, S; Pasanen, A; Meriranta, L; Karjalainen-Lindsberg, M-L; Nørgaard, P; Pedersen, M; Gang, AO; Høgdall, E; Heavican, TB; Lone, W; Iqbal, J; Qin, Q; Li, G; Kim, SY; Healy, J; Richards, KL; Fedoriw, Y; Bernal-Mizrachi, L; Koff, JL; Staton, AD; Flowers, CR; Paltiel, O; Goldschmidt, N; Calaminici, M; Clear, A; Gribben, J; Nguyen, E; Czader, MB; Ondrejka, SL; Collie, A; Hsi, ED; Tse, E; Au-Yeung, RKH; Kwong, Y-L; Srivastava, G et al.
October 1, 2017
Bouska, A; Bi, C; Lone, W; Zhang, W; Kedwaii, A; Heavican, T; Lachel, CM; Yu, J; Ferro, R; Eldorghamy, N; Greiner, TC; Vose, J; Weisenburger, DD; Gascoyne, RD; Rosenwald, A; Ott, G; Campo, E; Rimsza, LM; Jaffe, ES; Braziel, RM; Siebert, R; Miles, RR; Dave, S; Reddy, A; Delabie, J; Staudt, LM; Song, JY; McKeithan, TW; Fu, K; Green, M; Chan, WC; Iqbal, J
October 1, 2017
Huang, J; Chen, M; Whitley, MJ; Kuo, H-C; Xu, ES; Walens, A; Mowery, YM; Van Mater, D; Eward, WC; Cardona, DM; Luo, L; Ma, Y; Lopez, OM; Nelson, CE; Robinson-Hamm, JN; Reddy, A; Dave, SS; Gersbach, CA; Dodd, RD; Kirsch, DG
July 10, 2017
Guo, X; Koff, JL; Moffitt, AB; Cinar, M; Ramachandiran, S; Chen, Z; Switchenko, JM; Mosunjac, M; Neill, SG; Mann, KP; Bagirov, M; Du, Y; Natkunam, Y; Khoury, HJ; Rossi, MR; Harris, W; Flowers, CR; Lossos, IS; Boise, LH; Dave, SS; Kowalski, J; Bernal-Mizrachi, L
July 1, 2017
Bouchlaka, MN; Moffitt, AB; Kim, J; Kink, JA; Bloom, DD; Love, C; Dave, S; Hematti, P; Capitini, CM
June 1, 2017
Moffitt, AB; Ondrejka, SL; McKinney, M; Rempel, RE; Goodlad, JR; Teh, CH; Leppa, S; Mannisto, S; Kovanen, PE; Tse, E; Au-Yeung, RKH; Kwong, Y-L; Srivastava, G; Iqbal, J; Yu, J; Naresh, K; Villa, D; Gascoyne, RD; Said, J; Czader, MB; Chadburn, A; Richards, KL; Rajagopalan, D; Davis, NS; Smith, EC; Palus, BC; Tzeng, TJ; Healy, JA; Lugar, PL; Datta, J; Love, C; Levy, S; Dunson, DB; Zhuang, Y; Hsi, ED; Dave, SS
May 1, 2017