Charles A Gersbach, PhD

Charlie Gersbach
2353C CIEMAS Durham, NC 27710

Charles A Gersbach, PhD

John W. Strohbehn Distinguished Professor of Biomedical Engineering

We are particularly interested in developing and applying technologies that manipulate cellular processes at the genetic level.

The Gersbach Lab is focused on engineering new methods for directing cell behavior to regenerate diseased or damaged tissues and treat genetic diseases. Our work capitalizes on the products of the Genomic Revolution and modern advances in the fields of genetic reprogramming, gene delivery, protein engineering, stem cell transplantation, and synthetic biology to create innovative biologic approaches to improving human health. These studies also facilitate a better understanding of complex processes including organogenesis, cell lineage determination, and gene regulation that will ultimately lead to improved design of drugs and biotherapeutics. Our efforts are catalyzed by interdisciplinary collaborations with investigators in engineering and medicine at Duke and other institutions.

Charles Gersbach is a Rooney Family Associate Professor of Biomedical Engineering. Dr. Gersbach received his Ph.D. from Georgia Institute of Technology in 2006. He is also a member of the Duke Cancer Institute and an affiliate of the Duke Initiative for Science and Society.  

Research Interests

Regenerative medicine
Gene therapy
Genome engineering
Protein engineering

Recent Publications

Seo, J; Koçak, DD; Bartelt, LC; Williams, CA; Barrera, A; Gersbach, CA; Reddy, TE
April 1, 2021
Saha, K; Sontheimer, EJ; Brooks, PJ; Dwinell, MR; Gersbach, CA; Liu, DR; Murray, SA; Tsai, SQ; Wilson, RC; Anderson, DG; Asokan, A; Banfield, JF; Bankiewicz, KS; Bao, G; Bulte, JWM; Bursac, N; Campbell, JM; Carlson, DF; Chaikof, EL; Chen, Z-Y; Cheng, RH; Clark, KJ; Curiel, DT; Dahlman, JE; Deverman, BE; Dickinson, ME; Doudna, JA; Ekker, SC; Emborg, ME; Feng, G; Freedman, BS; Gamm, DM; Gao, G; Ghiran, IC; Glazer, PM; Gong, S; Heaney, JD; Hennebold, JD; Hinson, JT; Khvorova, A; Kiani, S; Lagor, WR; Lam, KS; Leong, KW; Levine, JE; Lewis, JA; Lutz, CM; Ly, DH; Maragh, S; McCray, PB; McDevitt, TC; Mirochnitchenko, O; Morizane, R; Murthy, N; Prather, RS; Ronald, JA; Roy, S; Roy, S; Sabbisetti, V; Saltzman, WM; Santangelo, PJ; Segal, DJ; Shimoyama, M; Skala, MC; Tarantal, AF; Tilton, JC; Truskey, GA; Vandsburger, M; Watts, JK; Wells, KD; Wolfe, SA; Xu, Q; Xue, W; Yi, G; Zhou, J; SCGE Consortium,
April 1, 2021
Walejko, JM; Christopher, BA; Crown, SB; Zhang, G-F; Pickar-Oliver, A; Yoneshiro, T; Foster, MW; Page, S; van Vliet, S; Ilkayeva, O; Muehlbauer, MJ; Carson, MW; Brozinick, JT; Hammond, CD; Gimeno, RE; Moseley, MA; Kajimura, S; Gersbach, CA; Newgard, CB; White, PJ; McGarrah, RW
March 15, 2021
Kwon, JB; Ettyreddy, AR; Vankara, A; Bohning, JD; Devlin, G; Hauschka, SD; Asokan, A; Gersbach, CA
December 11, 2020
Black, JB; McCutcheon, SR; Dube, S; Barrera, A; Klann, TS; Rice, GA; Adkar, SS; Soderling, SH; Reddy, TE; Gersbach, CA
December 1, 2020
Bulaklak, K; Gersbach, CA
November 16, 2020