2006 Publications

2006 Publications

Oncogenic pathway signatures in human cancers as a guide to targeted therapies.
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, Joshi MB, Harpole D, Lancaster JM, Berchuck A, Olson JA, Marks JR, Dressman HK, West M, Nevins JR
Nature.439(7074):353-7

Focusing on pathways to address complex biological and clinical phenotypes.
Bild, A., Potti, A, and Nevins, JR
Nat. Rev. Cancer .6: 735-741

Transcriptional origin of Kaposi's sarcoma-associated herpesvirus microRNAs
Cai X, Cullen BR.
J Virol.80(5):2234-42

GATHER: a systems approach to interpreting genomic signatures.
Chang, JT and Nevins, JR
Bioinformatics.22:2926-33

Genomic prediction of locoregional recurrence after mastectomy in breast cancer.
Cheng SH, Horng CF, West M, Huang E, Pittman J, Tsou MH, Dressman H, Chen CM, Tsai SY, Jian JJ, Liu MC, Nevins JR, Huang AT
J Clin Oncol.24(28):4594-602

Molecular profile and partial functional analysis of novel endothelial cell derived growth factors that regulate hematopoiesis.
Chute JP, Muramoto GG, Dressman HK, Wolfe G, Chao NJ, Lin S
Stem Cells.24(5):1315-27

Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans
Cramer, KL, Gerrald QD, Nichols CB, Price MS, Alspaugh AJ
Eukaryot Cell .5: 1147-1156

Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure.
Damodaran TV, Patel AG, Greenfiled ST, Dressman HK, Lin SM, Abou-Donia MB
Biochem Pharmacol.71(4):497-520

Toxicogenomic studies of the rat brain at an early time point following acute sarin exposure
Damodaran TV, Greenfield ST, Patel AG, Dressman HK, Lin SM, Abou-Donia MB
Neurochem Res.31(3):367-81

Toll-like receptor 2-dependent and �Cindependent activation of macrophages by group B streptococci
Draper DW, Bethea HN, He YW
Immunology Letters .102:202-214

Assessing incomplete deprotection of microarray oligonucleotides in situ
Dressman HK, Barley-Maloney, L, Rowlette, LL, Agris, PF, and Garcia-Blanco MA
NAR.34:e131

Genomic signatures in non-small cell lung cancer: targeting the targeted therapies
Dressman HK, Bild A, Garst J, Harpole D, Potti A
Current Oncology Reports .8:252-257

Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy
Dressman HK, Hans C, Bild A, Marks J, Olson JA, Rosen E, Marcom PK, Liotcheva V, Jones E, Vujaskovic Z, Dewhirst MW, West M, Nevins JR, Blackwell KL
Clin. Cancer Res.12:819-26

Application of oligonucleotide microarrays to assess the biological effects of neoadjuvant imatinib mesylate treatment for localized prostate cancer
Febbo PG, Thorner A, Rubin MA, Loda M, Kantoff PW, Oh WK, Golub T, George D
Clin Cancer Res.12(1):152-8

Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma.
Gollob JA, Sciambi CJ, Peterson BL, Richmond T, Thoreson M, Moran K, Dressman HK, Jelinek J, Issa JP
Clin Cancer Res.12(15):4619-27

Characterization of free-floating spheres from human trabecular meshwork (HTM) cell culture in vitro
Gonzalez P, Epstein DL, Luna C, Liton PB
Exp Eye Res.82(6):959-67

Linking ligand-induced alterations in androgen receptor structure to differential gene expression: a first step in the rational design of selective androgen receptor modulators
Kazmin D, Prytkova T, Cook CE, Wolfinger R, Chu TM, Beratan D, Norris JD, Chang CY, McDonnell DP
Mol Endocrinol.20(6):1201-17

Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system
Kiang A, Hartman ZC, Everett RS, Serra D, Jiang H, Frank MM, Amalfitano A.
Mol Ther .14(4):588-98

PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K.
Kwiek NC, Thacker DF, Datto MB, Megosh HB, Haystead TA
Cell Signal.18(10):1769-78

Identification of genes associated with ovarian cancer metastasis using microarray expression analysis
Lancaster JM, Dressman HK, Clarke JP, Sayer RA, Martino MA, Cragun JM, Henriott AH, Gray J, Sutphen R, Elahi A, Whitaker RS, West M, Marks JR, Nevins JR, Berchuck A
Int J Gynecol Cancer.16(5):1733-45

High expression of insulin-like growth factor binding protein-2 messenger RNA in epithelial ovarian cancers produces elevated preoperative serum levels
Lancaster JM, Sayer RA, Blanchette C, Calingaert B, Konidari I, Gray J, Schildkraut J, Schomberg DW, Marks JR, Berchuck A
Int J Gynecol Cancer.16(4):1529-35

Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T-cells in Patients with Malignant Glioma Reveals Differential Expression of the Immunologic Transcriptome Compared to T-cells from Healthy Volunteers
Learn CA, Fecci PE, Schmittling RJ, Xie W, Karikari I, Mitchell DA, Archer GE, Wei Z, Dressman H, Sampson JH
Clin Cancer Res.12:7306-15

Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.
Lee JY, Colinas J, Wang JY, Mace D, Ohler U, Benfey PN
PNAS.103:6055-60

Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis
Levesque MP, Vernoux T, Busch W, Cui H, Wang JY, Blilou I, Hassan H, Nakajima K, Matsumoto N, Lohmann JU, Scheres B, Benfey PN
PLoS Biol..4(5):e143

Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue
Liton PB, Luna C, Challa P, Epstein DL, Gonzalez P
Mol Vis .12:774-90

Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue.
Liton PB, Luna C, Challa P, Epstein DL, Gonzalez P
Mol Vis. .12:774-90

ALK1 signaling analysis identifies angiogenesis related genes and reveals disparity between TGF-b and constitutively active receptor induced gene expression.
Lux A, Salway F, Dressman HK, Kroener-Lux G, Hafner M, Day PJ, Marchuk DA, Garland J
BMC Cardiovasc Disord.6(1):13

Quantification of transcription factor expression from Arabidopsis images
Mace DL, Lee JY, Twigg RW, Colinas J, Benfey PN, Ohler U
Bioinformatics.22:e323-31

A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity
Mosher RA, Durrant WE, Wang D, Song J, Dong X
Plant Cell.18(7):1750-65

Sox2 is required for development of taste bud sensory cells.
Okubo T, Pevny LH, Hogan BL
Genes Dev.20(19):2654-9

Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase
Shianna KV, Marchuk DA, Strand MK
Mitochondrion.(2):94-101

A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes.
Wada K, Howard JT, McConnell P, Whitney O, Lints T, Rivas MV, Horita H, Patterson MA, White SA, Scharff C, Haesler S, Zhao S, Sakaguchi H, Hagiwara M, Shiraki T, Hirozane-Kishikawa T, Skene P, Hayashizaki Y, Caminci P, Jarvis ED.
PNAS.103(41):15212-7

Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness
Walker JK, Ahumada A, Frank B, Gaspard R, Berman K, Quackenbush J, Schwartz DA
Am J Respir Cell Mol Biol.34(6):711-8

A genomic approach to identify regulatory nodes in the transcriptional network of systemic acquired resistance in plants.
Wang D, Amornisiripanitch N, Dong X
PLoS Pathog.2:e123