Proteomics provides qualitative and quantitative information on the direct products of gene expression - proteins. Differential expression proteomics characterizes changes in the proteome due to biological challenges such as genotype, disease state and drug treatment. Additional applications include characterization of protein:protein interactions and biomarker identification.
- Full support: Experimental design, sample preparation, sample analysis and initial data analysis
- State-of-the-art LC/MS/MS based technology using rigorous quality control metrics
- Technology applicable to cell lines, tissues and biofluids
- Cell lines and tissues yield coverage for several thousand proteins without fractionation; up to ~8,000 proteins with isobaric tagging and fractionation
Embryo Samples: 14,351 peptides and 3,362 proteins
Principal Component Analysis
Expression results Z-score normalized with 2D Agglomerative Cluser Analysis
Workflow
- Sample Preparation
- LC/MS/MS
- Data Workup