Publications

Collaborative Publications

2018

Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Toleman CA, Schumacher MA, Yu SH, Zeng W, Cox NJ, Smith TJ, Soderblom EJ, Wands AM, Kohler JJ, Boyce M. Proc Natl Acad Sci U S A. 2018 May 21. pii: 201722437. doi: 10.1073/pnas.1722437115. PMID: 29784830


Proteomics and immunohistochemistry identify the expression of α-cardiac myosin heavy chain in the jaw-closing muscles of sooty mangabeys (order Primates). Wall CE, Holmes M, Soderblom EJ, Taylor AB. Arch Oral Biol. 2018 Jul;91:103-108. doi: 10.1016/j.archoralbio.2018.01.019. Epub 2018 Feb 3. PMID: 29703519


CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. Lin CC, Kitagawa M, Tang X, Hou MH, Wu J, Qu DC, Srinivas V, Liu X, Thompson JW, Mathey-Prevot B, Yao TP, Lee SH, Chi JT. Nat Commun. 2018 Mar 12;9(1):1039. doi: 10.1038/s41467-018-03422-6.
PMID: 29531224


The canine MHC class Ia allele DLA-88*508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif.
Ross P, Nemec PS, Kapatos A, Miller KR, Holmes JC, Suter SE, Buntzman AS, Soderblom EJ, Collins EJ, Hess PR.
Vet Immunol Immunopathol. 2018 Mar;197:76-86. doi: 10.1016/j.vetimm.2018.01.005. Epub 2018 Feb 2.
PMID: 29475511


Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs. Juvvadi PR, Moseley MA, Hughes CJ, Soderblom EJ, Lennon S, Perkins SR, Thompson JW, Geromanos SJ, Wildgoose J, Richardson K, Langridge JI, Vissers JPC, Steinbach WJ.
J Proteome Res. 2018 Feb 2;17(2):780-793. doi: 10.1021/acs.jproteome.7b00499. Epub 2017 Dec 29.
PMID: 29251506


The tail domain of the <i>Aspergillus fumigatus</i> class V myosin MyoE orchestrates septal localization and hyphal growth.
Renshaw H, Vargas-Muñiz JM, Juvvadi PR, Richards AD, Waitt G, Soderblom EJ, Moseley MA, Steinbach WJ. J Cell Sci. 2018 Feb 7;131(3). pii: jcs205955. doi: 10.1242/jcs.205955. PMID: 29222113


Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization. Moseley MA, Hughes CJ, Juvvadi PR, Soderblom EJ, Lennon S, Perkins SR, Thompson JW, Steinbach WJ, Geromanos SJ, Wildgoose J, Langridge JI, Richardson K, Vissers JPC. J Proteome Res. 2018 Feb 2;17(2):770-779. doi: 10.1021/acs.jproteome.7b00464. Epub 2017 Dec 29.
PMID: 28901143


Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway.
Cox NJ, Unlu G, Bisnett BJ, Meister TR, Condon BM, Luo PM, Smith TJ, Hanna M, Chhetri A, Soderblom EJ, Audhya A, Knapik EW, Boyce M. Biochemistry. 2018 Jan 9;57(1):91-107. doi: 10.1021/acs.biochem.7b00870. Epub 2017 Dec 15. PMID: 29161034


2017

New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report.
Bowler RP, Wendt CH, Fessler MB, Foster MW, Kelly RS, Lasky-Su J, Rogers AJ, Stringer KA, Winston BW; American Thoracic Society Workgroup on Metabolomics and Proteomics. Ann Am Thorac Soc. 2017 Dec;14(12):1721-1743. doi: 10.1513/AnnalsATS.201710-770WS. PMID: 29192815


Phosphorylation of Aspergillus fumigatus PkaR impacts growth and cell wall integrity through novel mechanisms. Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Moseley MA, Nicely NI, Steinbach WJ. FEBS Lett. 2017 Nov;591(22):3730-3744. doi: 10.1002/1873-3468.12886. Epub 2017 Nov 9. PMID: 29067690


Targeted metabolomics and medication classification data from participants in the ADNI1 cohort.
St John-Williams L, Blach C, Toledo JB, Rotroff DM, Kim S, Klavins K, Baillie R, Han X, Mahmoudiandehkordi S, Jack J, Massaro TJ, Lucas JE, Louie G, Motsinger-Reif AA, Risacher SL; Alzheimer’s Disease Neuroimaging Initiative; Alzheimer’s Disease Metabolomics Consortium, Saykin AJ, Kastenmüller G, Arnold M, Koal T, Moseley MA, Mangravite LM, Peters MA, Tenenbaum JD, Thompson JW, Kaddurah-Daouk R. Sci Data. 2017 Oct 17;4:170140. doi: 10.1038/sdata.2017.140. PMID: 29039849


The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.
Baek AE, Yu YA, He S, Wardell SE, Chang CY, Kwon S, Pillai RV, McDowell HB, Thompson JW, Dubois LG, Sullivan PM, Kemper JK, Gunn MD, McDonnell DP, Nelson ER. Nat Commun. 2017 Oct 11;8(1):864. doi: 10.1038/s41467-017-00910-z.
PMID: 29021522


Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma. Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S. J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6.
PMID: 28986437


Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration. Banks CJ, Rodriguez NW, Gashler KR, Pandya RR, Mortenson JB, Whited MD, Soderblom EJ, Thompson JW, Moseley MA, Reddi AR, Tessem JS, Torres MP, Bikman BT, Andersen JL.Mol Cell Biol. 2017 Sep 26;37(20). pii: e00354-17. doi: 10.1128/MCB.00354-17. Print 2017 Oct 15.
PMID: 28739857


Correction to "Proteomic Characterization of the Cellular Response to Nitrosative Stress Mediated by S-Nitrosoglutathione Reductase Inhibition". Foster MW, Yang Z, Gooden DM, Thompson JW, Ball CH, Turner ME, Hou Y, Pi J, Moseley MA, Que LG. J Proteome Res. 2017 Jul 7;16(7):2661. doi: 10.1021/acs.jproteome.7b00368. Epub 2017 Jun 19. PMID: 28627176


Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Kimbung S, Chang CY, Bendahl PO, Dubois L, Thompson JW, McDonnell DP, Borgquist S. Endocr Relat Cancer. 2017 Jul;24(7):339-349. doi: 10.1530/ERC-16-0533. Epub 2017 Apr 25.
PMID: 28442559


SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion. Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD. Cell Metab. 2017 Apr 4;25(4):838-855.e15. doi: 10.1016/j.cmet.2017.03.003. PMID: 28380376


Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus.  Vargas-Muñiz JM, Renshaw H, Waitt G, Soderblom EJ, Moseley MA, Palmer JM, Juvvadi PR, Keller NP, Steinbach WJ. Biochem Biophys Res Commun. 2017 Apr 1;485(2):221-226. doi: 10.1016/j.bbrc.2017.02.116. Epub 2017 Feb 24. PMID: 28238781


A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.  Wagner GR, Bhatt DP, O'Connell TM, Thompson JW, Dubois LG, Backos DS, Yang H, Mitchell GA, Ilkayeva OR, Stevens RD, Grimsrud PA, Hirschey MD.  Cell Metab. 2017 Apr 4;25(4):823-837.e8. doi: 10.1016/j.cmet.2017.03.006.  PMID: 28380375


The Diacetyl-exposed Human Airway Epithelial Secretome: New Insights Into Flavoring Induced Airways Disease. Brass DM, Gwinn WM, Valente AM, Kelly FL, Brinkley CD, Nagler AE, Moseley MA, Morgan DL, Palmer SM, Foster MW. Am J Respir Cell Mol Biol. 2017 Mar 1. doi: 10.1165/rcmb.2016-0372OC. [Epub ahead of print] PMID: 28248570


Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis.  Wang L, Ko ER, Gilchrist JJ, Pittman KJ, Rautanen A, Pirinen M, Thompson JW, Dubois LG, Langley RJ, Jaslow SL, Salinas RE, Rouse DC, Moseley MA, Mwarumba S, Njuguna P, Mturi N; Wellcome Trust Case Control Consortium 2.; Kenyan Bacteraemia Study Group., Williams TN, Scott JA, Hill AV, Woods CW, Ginsburg GS, Tsalik EL, Ko DC.  Sci Adv. 2017 Mar 8;3(3):e1602096. doi: 10.1126/sciadv.1602096. eCollection 2017 Mar.  PMID: 28345042


Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke. Tu TM, Kolls BJ, Soderblom EJ, Cantillana V, Ferrell PD, Moseley MA, Wang H, Dawson HN, Laskowitz DT. Ann Clin Transl Neurol. 2017 Mar 9;4(4):246-265. doi: 10.1002/acn3.399. eCollection 2017 Apr. PMID: 28382306


Metabolic network failures in Alzheimer's disease-A biochemical road map.  Toledo JB, Arnold M, Kastenmüller G, Chang R, Baillie RA, Han X, Thambisetty M, Tenenbaum JD, Suhre K, Thompson JW, John-Williams LS, MahmoudianDehkordi S, Rotroff DM, Jack JR, Motsinger-Reif A, Risacher SL, Blach C, Lucas JE, Massaro T, Louie G, Zhu H, Dallmann G, Klavins K, Koal T, Kim S, Nho K, Shen L, Casanova R, Varma S, Legido-Quigley C, Moseley MA, Zhu K, Henrion MY, van der Lee SJ, Harms AC, Demirkan A, Hankemeier T, van Duijn CM, Trojanowski JQ, Shaw LM, Saykin AJ, Weiner MW, Doraiswamy PM, Kaddurah-Daouk R; Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium. Alzheimers Dement. 2017 Mar 21. pii: S1552-5260(17)30046-8. doi: 10.1016/j.jalz.2017.01.020. [Epub ahead of print] PMID: 28341160


Probing the Allosteric Role of the α5 Subunit of α3β4α5 Nicotinic Acetylcholine Receptors by Functionally Selective Modulators and Ligands. Ray C, Soderblom EJ, Bai Y, Carroll FI, Caron MG, Barak LS. ACS Chem Biol. 2017 Mar 17;12(3):702-714. doi: 10.1021/acschembio.6b01117. Epub 2017 Jan 24. PMID: 28045487


Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection.  Burke TW, Henao R, Soderblom E, Tsalik EL, Thompson JW, McClain MT, Nichols M, Nicholson BP, Veldman T, Lucas JE, Moseley MA, Turner RB, Lambkin-Williams R, Hero AO 3rd, Woods CW, Ginsburg GS. EBioMedicine. 2017 Mar;17:172-181. doi: 10.1016/j.ebiom.2017.02.015. Epub 2017 Feb 21. PMID: 28238698


A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus.  Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Moseley MA, Nicely NI, Asfaw YG, Steinbach WJ. MBio. 2017 Feb 7;8(1). pii: e02319-16. doi: 10.1128/mBio.02319-16. PMID: 28174315


Vagal nerve stimulation modifies neuronal activity and the proteome of excitatory synapses of amygdala/piriform cortex. Alexander GM, Huang YZ, Soderblom EJ, He XP, Moseley MA, McNamara JO. J Neurochem. 2017 Feb;140(4):629-644. doi: 10.1111/jnc.13931. Epub 2017 Feb 3. PMID: 27973753


CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.  Alfaqih MA, Nelson ER, Liu W, Safi R, Jasper JS, Macias E, Geradts J, Thompson JW, Dubois LG, Freeman MR, Chang CY, Chi JT, McDonnell DP, Freedland SJ.  Cancer Res. 2017 Apr 1;77(7):1662-1673. doi: 10.1158/0008-5472.CAN-16-2738. Epub 2017 Jan 27. PMID: 28130224


Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl. Foster MW, Gwinn WM, Kelly FL, Brass DM, Valente AM, Moseley MA, Thompson JW, Morgan DL, Palmer SM. J Proteome Res. 2017 Feb 3;16(2):538-549. doi: 10.1021/acs.jproteome.6b00672. Epub 2017 Jan 9.  PMID: 27966365


2016

Oral microbiome diversity among Cheyenne and Arapaho individuals from Oklahoma. Ozga AT, Sankaranarayanan K, Tito RY, Obregon-Tito AJ, Foster MW, Tallbull G, Spicer P, Warinner CG, Lewis CM Jr. Am J Phys Anthropol. 2016 Oct;161(2):321-7. doi: 10.1002/ajpa.23033. Epub 2016 Jun 30. PMID: 27357925


Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage. Lei B, James ML, Liu J, Zhou G, Venkatraman TN, Lascola CD, Acheson SK, Dubois LG, Laskowitz DT, Wang H. Sci Rep. 2016 Oct 7;6:34834. doi: 10.1038/srep34834. PMID: 27713572


Corrigendum: Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI). Peterson CT, Lucas J, John-Williams LS, Thompson JW, Moseley MA, Patel S, Peterson SN, Porter V, Schadt EE, Mills PJ, Tanzi RE, Doraiswamy PM, Chopra D. Sci Rep. 2016 Oct 10;6:34678. doi: 10.1038/srep34678. No abstract available. PMID: 27721380


Calcineurin Targets Involved in Stress Survival and Fungal Virulence. Park HS, Chow EW, Fu C, Soderblom EJ, Moseley MA, Heitman J, Cardenas ME. PLoS Pathog. 2016 Sep 9;12(9):e1005873. doi: 10.1371/journal.ppat.1005873. eCollection 2016 Sep. PMID: 27611567


Identification of an elaborate complex mediating postsynaptic inhibition.  Uezu A, Kanak DJ, Bradshaw TW, Soderblom EJ, Catavero CM, Burette AC, Weinberg RJ, Soderling SH.  Science. 2016 Sep 9;353(6304):1123-9. doi: 10.1126/science.aag0821. PMID: 27609886


Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection. Feger BJ, Thompson JW, Dubois LG, Kommaddi RP, Foster MW, Mishra R, Shenoy SK, Shibata Y, Kidane YH, Moseley MA, Carnell LS, Bowles DE. Sci Rep. 2016 Sep 27;6:34091. doi: 10.1038/srep34091. PMID: 27670941


Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI). Peterson CT, Lucas J, John-Williams LS, Thompson JW, Moseley MA, Patel S, Peterson SN, Porter V, Schadt EE, Mills PJ, Tanzi RE, Doraiswamy PM, Chopra DSci Rep. 2016 Sep 9;6:32609. doi: 10.1038/srep32609.  PMID: 27611967


Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats. Quinones QJ, Zhang Z, Ma Q, Smith MP, Soderblom E, Moseley MA, Bain J, Newgard CB, Muehlbauer MJ, Hirschey M, Drew KL, Barnes BM, Podgoreanu MV. Anesthesiology. 2016 Jun;124(6):1296-310. PMID: 27187119.


Dephosphorylation of the Core Septin, AspB, in a Protein Phosphatase 2A-Dependent Manner Impacts Its Localization and Function in the Fungal Pathogen Aspergillus fumigatus. Vargas-Muñiz JM, Renshaw H, Richards AD, Waitt G, Soderblom EJ, Moseley MA, Asfaw Y, Juvvadi PR, Steinbach WJ. Front Microbiol. 2016 Jun 22;7:997. doi: 10.3389/fmicb.2016.00997. eCollection 2016. PMID: 27446037


Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2+ Breast Cancer. Alwarawrah Y, Hughes P, Loiselle D, Carlson DA, Darr DB, Jordan JL, Xiong J, Hunter LM, Dubois LG, Thompson JW, Kulkarni MM, Ratcliff AN, Kwiek JJ, Haystead TA. Cell Chem Biol. 2016 May 27. PMID: 27265747.


Comprehensive proteomic and metabolomic signatures of nontypeable Haemophilus influenzae-induced acute otitis media reveal bacterial aerobic respiration in an immunosuppressed environment. Harrison A, Dubois LG, St John-Williams L, Moseley MA 3rd, Hardison RL, Heimlich DR, Stoddard A, Kerschner JE, Justice SS, Thompson JW, Mason KM. Mol Cell Proteomics. 2016 Mar;15(3):1117-38. doi: 10.1074/mcp.M115.052498. Epub 2015 Dec 28. PMID: 26711468.


Genetic Variation in Surfactant Protein-A2 Results in Altered Regulation of Eosinophil Activities and Enhanced Eosinophilia in Patients with Asthma. Ledford JG, Addison KJ, Francisco D, Foster MW, Voelker DR, Que LG, Kraft M. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S101. doi: 10.1513/AnnalsATS.201508-520MG. No abstract available. PMID: 27027938


The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins. Davies MN, Kjalarsdottir L, Thompson JW, Dubois LG, Stevens RD, Ilkayeva OR, Brosnan MJ, Rolph TP, Grimsrud PA, Muoio DM. Cell Rep. 2016 Jan 12;14(2):243-54. PMID: 26748706.


Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication. Phillips SL, Soderblom EJ, Bradrick SS, Garcia-Blanco MA. MBio. 2016 Jan 5;7(1). pii: e01865-15. doi: 10.1128/mBio.01865-15. PMID: 26733069.


2015

BNIP3 Promotes Calcium and Calpain-Dependent Cell Death. Graham RM, Thompson JW, Webster KA. Life Sci. 2015 Dec 1;142:26-35. doi: 10.1016/j.lfs.2015.10.010. Epub 2015 Oct 21. PMID: 26471219.


Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle. Barrientos T, Laothamatas I, Koves TR, Soderblom EJ, Bryan M, Moseley MA, Muoio DM, Andrews NC. EBioMedicine. 2015 Oct 4;2(11):1705-17. eCollection 2015 Nov. PMID: 26870796.


Optimizing Urine Processing Protocols for Protein and Metabolite Detection. Nazema Y Siddiqui, Laura G BuBois, Lisa St John-Williams, Will Thompson, Carole Grenier, Emily Burke, Matthew O Fraser, Dincy L Amundsen and Susan K Murphy. Journal of Proteomics and Bioinformatics. 2015 Dec 21. doi:10.4172/jpb.S14-003. 


The 2012/2013 ABRF Proteomic Research Group Study: Assessing Longitudinal Intralaboratory Variability in Routine Peptide Liquid Chromatography Tandem Mass Spectrometry Analyses. Bennett KL, Wang X, Bystrom CE, Chambers MC, Andacht TM, Dangott LJ, Elortza F, Leszyk J, Molina H, Moritz RL, Phinney BS, Thompson JW, Bunger MK, Tabb DL. Mol Cell Proteomics. 2015  Dec;14(12):3299-309. doi: 10.1074/mcp.O115.051888. Epub 2015 Oct 4. PMID: 26435129.


S-Nitrosylation of Sarcomeric Proteins Depresses Myofilament Ca(2+) Sensitivity in Intact Cardiomyocytes. Figueiredo-Freitas C, Dulce RA, Foster MW, Liang J, Yamashita AM, Lima-Rosa FL, Thompson JW, Moseley MA, Hare JM, Nogueira L, Sorenson MM, Pinto JR. Antioxid Redox Signal. 2015 Nov 1;23(13):1017-34. doi: 10.1089/ars.2015.6275. PMID: 26421519.


Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures. Foster MW, Gerhardt G, Robitaille L, Plante PL, Boivin G, Corbeil J, Moseley MA. Anal Chem. 2015 Oct 20;87(20):10247-54. doi: 10.1021/acs.analchem.5b01544. Epub 2015 Sep 29. PMID: 26376123.


Transcription errors induce proteotoxic stress and shorten cellular lifespan. Vermulst M, Denney AS, Lang MJ, Hung CW, Moore S, Moseley MA, Thompson JW, Madden V, Gauer J, Wolfe KJ, Summers DW, Schleit J, Sutphin GL, Haroon S, Holczbauer A, Caine J, Jorgenson J, Cyr D, Kaeberlein M, Strathern JN, Duncan MC, Erie DA. Nat Commun. 2015 Aug 25;6:8065. doi: 10.1038/ncomms9065. Erratum in: Nat Commun. 2015;6:8738. Thompson, William J and Mosely, Arthur M [Corrected to Thompson, J Will and Moseley, M Arthur]. PMID: 26304740.


Evolutionary Divergence of Gene and Protein Expression in the Brains of Humans and Chimpanzees. Bauernfeind AL, Soderblom EJ, Turner ME, Moseley MA, Ely JJ, Hof PR, Sherwood CC, Wray GA, Babbitt CC. Genome Biol Evol. 2015 Jul 10;7(8):2276-88. doi: 10.1093/gbe/evv132. PMID: 26163674.


Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus. Juvvadi PR, Muñoz A, Lamoth F, Soderblom EJ, Moseley MA, Read ND, Steinbach WJ. Antimicrob Agents Chemother. 2015 Aug;59(8):4946-55. doi: 10.1128/AAC.00263-15. Epub 2015 Jun 8. PMID: 26055379.


The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence. Vargas-Muñiz JM, Renshaw H, Richards AD, Lamoth F, Soderblom EJ, Moseley MA, Juvvadi PR, Steinbach WJ. Fungal Genet Biol. 2015 Aug;81:41-51. doi: 10.1016/j.fgb.2015.05.014. Epub 2015 Jun 5. PMID: 26051489.


Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus. Lamoth F, Juvvadi PR, Soderblom EJ, Moseley MA, Steinbach WJ. Antimicrob Agents Chemother. 2015 Aug;59(8):4727-33. doi: 10.1128/AAC.00946-15. Epub 2015 May 26. PMID: 26014950.


Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells. Saka HA, Thompson JW, Chen YS, Dubois LG, Haas JT, Moseley A, Valdivia RH. PLoS One. 2015 Apr 24;10(4):e0124630. doi: 10.1371/journal.pone.0124630. eCollection 2015. PMID: 25909443.


Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesis. Tang X, Keenan MM, Wu J, Lin CA, Dubois L, Thompson JW, Freedland SJ, Murphy SK, Chi JT. PLoS Genet. 2015 Apr 7;11(4):e1005158. doi: 10.1371/journal.pgen.1005158. eCollection 2015 Apr. PMID: 25849282.

Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus. Juvvadi PR, Ma Y, Richards AD, Soderblom EJ, Moseley MA, Lamoth F, Steinbach WJ. Front Microbiol. 2015 Mar 13;6:175. doi: 10.3389/fmicb.2015.00175. eCollection 2015. PMID: 25821446.


Cerebrospinal fluid proteomics in children during induction for acute lymphoblastic leukemia: A pilot study. Priola GM, Foster MW, Deal AM, Richardson BM, Thompson JW, Blatt J. Pediatr Blood Cancer. 2015 Jul;62(7):1190-4. doi: 10.1002/pbc.25420. Epub 2015 Mar 23. PMID: 25809122.


Histone deacetylase 6 (HDAC6) promotes the pro-survival activity of 14-3-3ζ via deacetylation of lysines within the 14-3-3ζ binding pocket. Mortenson JB, Heppler LN, Banks CJ, Weerasekara VK, Whited MD, Piccolo SR, Johnson WE, Thompson JW, Andersen JL. J Biol Chem. 2015 May 15;290(20):12487-96. doi: 10.1074/jbc.M114.607580. Epub 2015 Mar 13. PMID: 25770209.


An assessment of human gastric fluid composition as a function of PPI usage. Foltz E, Azad S, Everett ML, Holzknecht ZE, Sanders NL, Thompson JW, Dubois LG, Parker W, Keshavjee S, Palmer SM, Davis RD, Lin SS. Physiol Rep. 2015 Jan 27;3(1). pii: e12269. doi: 10.14814/phy2.12269. Print 2015 Jan 1. PMID: 25626870.


Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches. Michelotti GA, Tucker A, Swiderska-Syn M, Machado MV, Choi SS, Kruger L, Soderblom E, Thompson JW, Mayer-Salman M, Himburg HA, Moylan CA, Guy CD, Garman KS, Premont RT, Chute JP, Diehl AM. Gut. 2015 Jan 16. pii: gutjnl-2014-308176. doi: 10.1136/gutjnl-2014-308176. [Epub ahead of print] PMID: 25596181.


Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis. Foster MW, Morrison LD, Todd JL, Snyder LD, Thompson JW, Soderblom EJ, Plonk K, Weinhold KJ, Townsend R, Minnich A, Moseley MA. J Proteome Res. 2015 Feb 6;14(2):1238-49. doi: 10.1021/pr501149m. Epub 2015 Jan 14. PMID: 25541672.


2014

Convergent transcriptional specializations in the brains of humans and song-learning birds.  Pfenning AR, Hara E, Whitney O, Rivas MV, Wang R, Roulhac PL, Howard JT, Wirthlin M, Lovell PV, Ganapathy G, Mouncastle J, Moseley MA, Thompson JW, Soderblom EJ, Iriki A, Kato M, Gilbert MT, Zhang G, Bakken T, Bongaarts A, Bernard A, Lein E, Mello CV, Hartemink AJ, Jarvis ED Science. 2014 Dec 12;346(6215):1256846.  PMID: 25504733.


Structure and DNA-binding traits of the transition state regulator AbrB. Olson AL, Tucker AT, Bobay BG, Soderblom EJ, Moseley MA, Thompson RJ, Cavanagh J. Structure. 2014 Nov 4;22(11):1650-6. doi: 10.1016/j.str.2014.08.018. Epub 2014 Oct 9. PMID: 25308864


Metabolic-stress-induced rearrangement of the 14-3-3ζ interactome promotes autophagy via a ULK1- and AMPK-regulated 14-3-3ζ interaction with phosphorylated Atg9. Weerasekara VK, Panek DJ, Broadbent DG, Mortenson JB, Mathis AD, Logan GN, Prince JT, Thomson DM, Thompson JW, Andersen JL. Mol Cell Biol. 2014 Dec;34(24):4379-88. doi: 10.1128/MCB.00740-14. Epub 2014 Sep 29. PMID: 25266655.


Hydrolytic function of Exo1 in mammalian mismatch repair. Shao H, Baitinger C, Soderblom EJ, Burdett V, Modrich P. Nucleic Acids Res. 2014 Jun;42(11):7104-12. doi: 10.1093/nar/gku420. Epub 2014 May 14. PMID: 24829455.


Ion Mobility-Derived Collision Cross Section As an Additional Measure for Lipid Fingerprinting and Identification. Paglia G, Angel P, Williams JP, Richardson K, Olivos HJ, Thompson JW, Menikarachchi L, Lai S, Walsh C, Moseley A, Plumb RS, Grant DF, Palsson BO, Langridge J, Geromanos S, Astarita G. Anal Chem. 2014 Dec 29. [Epub ahead of print]. PMID: 25494517.


Metablolic Control of Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII)-mediated Caspase-2 Suppression by the B55β/Protein Phosphatase 2A (PP2A). Huang B, Yang CS, Wojton J, Huang NJ, Chen C, Soderblom EJ, Zhang L, Kornbluth S. JBiol Chem.  2014 Dec 26;289(52):35882-90 PMID: 25378403.


Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure.  Schechter MA, Hsieh MK, Njoroge LW, Thompson JW, Soderblom EJ, Feger BJ, Troupes CD, Hershberger KA, Ilkayeva OR, Nagel WL, Landinez GP, Shah KM, Burns VA, Santacruz L, Hirschey MD, Foster MW, Milano CA, Moseley MA, Piacentino V 3rd, Bowles DE.  PLoS One.  2014 Aug 12;9(8):e104157.  PMID:25117565.


Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum.  Jagannathan S, Hsu JC, Reid DW, Chen Q, Thompson WJ, Moseley AM, Nicchitta CV. J Biol Chem.  2014 Sep 12;289(37):25907-24.  PMID: 25063809.


Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A.  Foster MW, Thompson JW, Ledford JG, Dubois LG, Hollingsworth JW, Francisco D, Tanyaratsrisakul S, Voelker DR, Kraft M, Moseley MA, Foster WM.  J Proteome Res. 2014 Jul 15.  PMID:25025725.


Proteomic Differences between Male and Female Anterior Cruciate Ligament and Patellar Tendon.  Little D, Thompson JW, Dubois LG, Ruch DS, Moseley MA, Guilak F. PLoS One  2014 May 12;9(5):e96526.  PMID: 24818782, PMCID: PMC4018326.


Ion Mobility Derived Collision Cross Sections to Support Metabolomics Applications.  Paglia G, Williams JP, Menikarachchi L, Thompson JW, Tyldesley-Worster R, Halldórsson S, Rolfsson O, Moseley A, Grant D, Langridge J, Palsson BO, Astartita G. Anal Chem. 2014. Mar 28.  PMID: 24640936, PMCID: PM4004193.


Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia.  Iwabuchi M, Sheng H, Thompson JW, Wang L, Dubois LG, Gooden D, Moseley M, Paschen W, Yang W.  JCereb Blood Flow Metab.  2014 Mar;34(3):425-32.  PMID: 24301296, PMCID: PMC3948117.


Small Ubiquitin-Like Modifier 3-Modified Proteome Regulated by Brain Ischemia in Novel Small Ubiquitin-Like Modifier Transgenic Mice: Putative Protective Proteins/Pathways.  Yang W, Sheng H, Thompson JW, Zhao S, Wang L, Miao P, Liu X, Moseley MA, Paschen W.  Stroke.  2014 Feb. 25 PMID: 24569813, PMCID: PMC3966925.


Photo-Activated Psoralen Binds the ErbB2 Catalytic Kinase Domain, Blocking ErbB2 Signaling and Triggering Tumor Cell Apoptosis.  Xia W, Gooden D, Liu L, Zhao S, Soderblom EJ, Toone EJ, Beyer WF Jr, Walder H, Spector NL.  PLoS One.  2014 Feb 14;9(2).  PMID:24551203, PMCID: PMC 3925176.


A DNA Mimic: The Structure and Mechanism of Action for the Anti-Repressor Protein AbbA.  Tucker AT, Bobay BG, Banse AV, Olson AL, Soderblom EJ, Moseley MA, Thompson RJ, Varney KM, Losick R, Cavanagh J.  J Mol Biol.  2014 Feb 15 PMID: 24534728, PMCID: PMC4017629.


Identification of a Key Lysine Residue in the Heat Shock Protein 90 (Hsp90) Required for Azole and Echinocandin Resistance in Aspergillus fumigatus.  Lamoth F, Juvvadi PR, Soderblom EJ, Moseley MA, Asfaw YG, Steinbach WJ.  Antimicrob Agents Chemother.  2014 Jan 6 [Epub ahead of print].  PMID: 24395240, PMCID: PMC4023766.


Time-and concentration-dependent effects of exogenous serotonin and inflammatory cytokines on mast cell function.  Gruba SM, Meyer AF, Manning BM, Wany Y, Thompson JW, Dalluge JJ, Haynes CL.  ACS Chem Biol.  2014 Feb 21;9(2):503-9.  PMID: 24304209.

2013

Epsilon PKC increases brain mitochondrial SIRT1 protein levels via heat shock protein 90 following ischemic preconditioning in rats.  Thompson JW, Dave KR, Saul I, Narayanan SV, Perez-Pinzon MA.  PLoS One.  2013 Sep 13;8(9):e75753.  PMID:24058702.


A flexible statistical model for alignment of label-free proteomics data-incormporating ion mobility and product ion information.  Benjamin AM, Thompson JW, Soderblom EJ, Geromanos SJ, Henao R, Kraus VB, Moseley MA, Lucas JE.  BMC Bioinformatics.  2013 Dec 16;14:364.  doi: 10.1186/1471-2105-14-364.PMID:24341404, PMCID: PMC3878627.


Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus.  Juvvadi PR, Gehrke C, Fortwendel JR, Lamoth F, Soderblom EJ, Cook EC, Hast MA, Asfaw YG, Moseley MA, Creamer TP, Steinbach WJ. PLoS Pathog.  2013;9(8):e1003564 doi:10.1371/journal.ppat.  1003564.  Epub 2013 Aug 22.  PMID:23990785, PMCID: PMC3749960.


Charaterization of the ubiquitin-modified preteome regulated by transient forebrain ischemia.  Iwabuchi M, Sheng H, Thompson J, Wang L, Dubois LG, Gooden D, Moseley M, Paschen W, Yang WJ Cereb Blood Flow Metab.  2013 Dec 4.  doi: 10.1038/jcbfm.2013.210. [Epub ahead of print]


Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk.  Fouda GG, Jaeger FH, Amos JD, Ho C, Kunz EL, Anasti K, Stamper LW, Liebl BE, Barbas KH, Ohashi T, Moseley MA, Liao HX, Erickson HP, Alam SM, Permar SR.  Proc Natl Acad Sci USA.  2013 Nov 5; 110(45): 18220-5.  PMID:24145401 PMC3831436.


Identification of deacetylase subtrates with the biotins with approach.  Thompson JW, Robeson A, Andersen JL.  Methods Mol Biol. 2013; 1077:133-48.  PMID: 24014404.


Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase.  Hoos MD, Richardson BM, Foster MW, Everhart A, Thompson JW, Moseley MA, Colton C. J Proteome Res.  2013 Sep 4.  PMID: 24006891, PMCID: PMC3875406.


An integrated clinico-metabolomic model improves prediction of death in sepsis.  Langley RJ, Tsalik EL, Velkinburgh JC, et al.  Sci Transl Med.  2013 Jul 24;5(195) PMID: 23884467.


Proteomic Identification of Unique Photoreceptor Disc Components Reveals the Presence of PRCD, a Protein Linked to Retinal Degeneration.  Skiba NF, Spencer WJ, Salinas RY, Lieu EC, Thompson JW, Arshavsky VY.  J. Proteome Res.  2013 May 24.  PMID: 23672200, PMCID: PMC3771658.


Proteomic Analysis of Human Brochoalveolar Lavage Fluid After Subsegmental Exposure.  Foster MW, Thompson JJW, Que LG, Yang I, Schwartz D, Moseley MA, Marshall HE.  J.  Proteome Res.  2013 Apr 4.  PMID: 23550723, PMCID: PMC3822014.


Proteomic analysis of the NOS2 interactome in human airway epithelial cells.  Foster MW, Thompson JW, Forrester MT, Sha Y, McMahon TJ, Bowles DE, Moseley MA, Marshall HE.  Nitric Oxide.  2013 Feb 21.  pii: S1089-8603(13)00093-1.  PMID: 23438482, PMCID: PMC3769490.


Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus.  Juvvadi PR, Belina D, Soderblom EJ, Moseley MA, Steinbach WJ.  Biochem Biophys ResCommun.  2013 Feb 15; 431(3):547-53.  doi: 10.1016/j.bbrc.2013.01.020. Epub 2013 Jan 12. PMID: 23321313, [PubMed-in process] PMCID:PMC3587984.


Automated, Reproducible, Titania-Based Phosphopeptide Enrichment Strategy for Label-Free Quantitative Phosphoproteomics.  Richardson BR, Soderblom EJ, Thompson JW, Moseley MA. J. Biomol Tech.  2013 January: jbt. 13-2401-002.  Published online 2012 December 22.  doi: 10.7171/jbt.  13-2401-002, PMID: 23542237 [PubMed-in process] PMCID: PMC3533261.


Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation.  Soderblom EJ, Thompson JW, Schwartz EA, Chiou E, Dubois LG, Moseley MA, Zennadi R.  Clin Proteomics.  2013 Jan 3; 10(1):1.  PMID: 23286773, [PubMed] PMCID:  PMC3558407.

2012

NADPH Quinone Oxidoreductase 1 Regulates Host Susceptibility to Ozone via Isoprostane Generation.  Kummarapurugu AB, Fischer BM, Zheng S, Milne GL, Ghio AJ, Potts-Kant EN, Foster WM, Soderblom EJ, Dubois LG, Moseley MA, Thompson JW, Voynow JA.  J Biol Chem.  2012 Dec 28.  PMID:  23275341, PMCID: PMC3576073.


Proteomic analysis of an unculturable bacterial endosymbiont (Blochmannia) reveals high abundance of chaperonins and biosynthetic enzymes.  Fan Y, Thompson JW, Dubois LG, Moseley MA, Wernegreen JJ.  J Proteome Res.  2012 Dec 4.  PMID: 23205679, PMCID: PMC3599776.


Extraction and analysis of carnitine and acylcarnitines by electrospray ionization tandem mass spectrometry directly from dried blood and plasma spots using a novel autosampler.  Thompson JW, Zhang H, Smith P, Hillman S, Moseley MA, Millington DS.  Rapid Commun Mass Spectrom.  2012 Nov 15;26(21):2548-54.  PMID: 32008072, PMCID unavailable.


Solid-phase capture for the detection and relative quantification of S-nitrosoproteins by mass spectrometry.  Thompson JW, Forrester MT, Arthur Moseley M, Foster MW.  Methods.  2012 Oct 11.  pii: S1046-2023(12)00256-3.  PMID: 23064468, NIHMS414367.  PMCID: PMC3568208.


Plasma proteomics of patients with non-valvular atrial fibrillation on chronic anti-coagulation with warfarin or a direct factor Xa inhibitior. Chan MY, Lin M, Lucas J, Moseley A, Thompson JW, Cyr D, Ueda H, Kajikawa M, Ortel TL, Becker RC.  Thromb Haemost.  2012 Oct 10;108(6).  PMID: 23052711, PMCID unavailable.  


Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance.  Schumacher MA, Min J, Link TM, Guan Z, Xu W, Ahn YH, Soderblom EJ, Kurie JM, Evdokimov A, Moseley MA, Lewis K, Brennan RG.  Cell Rep.  2012 Sep 27;2(3): 518-25.  PMID: 22999936, PMCID unavailable.


Design and Application of a Data-Independent Precursor and Product Ion Repository.  Thalassinos K, Vissers JP, Tenzer S, Levin Y, Thompson JW, Daniel D, Mann D, Delong MR, Moseley MA, America AH, Ottens AK, Cavey GS, Efstathiou G, Scrivens JH, Langridge JI, Geromanos SJ.  J. Am Soc Mass Spectrom.  2012 July 31.  PMID: 22847389, PMCID unavailable.  


Abl Family Kinases Modulate T Cell-Mediated Inflammation and Chemokine-Induced Migration Through the Adaptor HEF1 and GTPase Rap1.  Gi JJ, Lavau CP, Soderblom EJ, Moseley MA, Pendergast AM.  Science Signaling 2012 5(233) July.  PMID: 22810897.  PMCID: PMC3602906.


Peptide Array X-Linking (PAX): A New Peptide-Protein Identification Approach.  Okada H, Uezu A, Soderblom EJ, Moseley MA, Gertler FB, Soderling SH  PLOS One.  2012 May 14; 7(5):  e37035.  PMID:  22606326, PMCID: PMC3351392.


Metaprotein expression modeling for label-free quantitative proteomics.  Lucas JE, Thompson JW, Dubois LG, McCarthy J, Tillmann H, Thompson A, Shire N, Hendrickson R, Dieguez F, Goldman P, Schwarz K, Patel K, McHutchison J, Moseley MA.  BMC Bioinformatics.  2012 May 4;13(1):74.  PMID: 22559859, PMCID: PMC3436780.


The protein expression landscape of the Arabidopsis root.  Petricka JJ, Schauer MA, Megraw M, Breakfield NW, Thompson JW, Georgiev S, Soderblom EJ, Ohler U, Moseley MA, Grossniklaus U, Benfey PN.  Proc Natl Acad Sci USA.  2012 Mar 23  PMID: 22447775, PMCID: PMC3344980.


Proteomic Characterization of the Cellular Response to Nitrosative Stress Mediated by S-Nitrosoglutathione Reductase Inhibition.  Foster MW, Yang Z, Gooden DM, Thompson JW, Ball C, Turner M, Hou Y, Pi J, Moseley MA, Que M D LG., J Proteome Res.  2012 Mar 5.  PMID: 22390303, PMCID: PMC3327136.


Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.  Zennadi R, Whalen EJ, Soderblom EJ, Alexander SC, Thompson JW, Dubois LG, Moseley MA, Telen MJ.  Blood.  2012 Feb 2;119(5): 1217-27.  PMID:  22147898, PMCID: PMC3327136.


Analysis of Oxygen/Glucose-Deprivation-Induces Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics.  Wang W, Thompson JW, Wang Z, Sheng H, Foster MW, Moseley MA, Paschen W. J.  Proteome Res.  2012 Feb. 3; 11(2): 1108-17.  PMID: 22082260, PMCID: PMC3628696.

2011

SH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexes.  Okada H, Uezu A, Mason FM, Soderblom EJ, Moseley MA 3rd, Soderling SH.  Sci Signal.  2011 Nov 29;4(201): rs13.  PMID: 22126966, PMCID: PMC3553496.


Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms.  Saka HA, Thompson JW, Chen YS, Kumar Y, Dubois LG, Moseley MA, Valdivia RH.  Mol Microbiol  2011 Dec;82(5):  1185-203.  PMID: 22126966, PMCID: PMC3225693.


Association of Calcineurin with the COPI Protein Sec28 and the COPII Protein Sec13 Revealed by Quantitative Proteomics.  Kozubowski L, Thompson JW, Cardenas ME, Moseley MA, Heitman J.  PLoS One  2011;6(10):e25280.  Epub 2011 Oct 3, PMCID: PMC3184950.


A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of sirt1 in the metabolic regulaton of caspase-2.  Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.  Mol Cell.  2011 Sept 2; 43(5): 834-42, PMID: 21884983, PMCID: PMC3417139.


Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation.  Melvin JA, Murhphy CF, Dubois LG, Thompson JW, Moseley MA, McCafferty DG.  Biochemistry.  2011 Sep 6;50(35): 7591-9.  PMID: 21812416, NIHMS317967, PMCID:PMC3604699.


Characterization of Serum Proteins Associated with IL28B Genotype among Patients with Chronic Hepatitis C.  Cyr DD, Lucas JE, Thompson JW, Patel K, Clark PJ, Thompson A, Tillmann HL, McHutchison JG, Moseley MA, McCarthy JJ.  PLoS One.  2011;6(7):e21854, PMID: 21750736, PMCID: PMC3130042.


Quantitative Label-Free Phosphoproteomics Strategy for Multifaceted Experimental Designs.  Soderblom EJ, Philipp M, Thompson JW, Caron MG, Moseley MA.  Anal Chem.  2011 Apr 22.  PMCID: PMC3093925.


High predictive accuracy of an unbiased proteomic profiled for sustained virologic response in chronic hepatitis C patients.  Patel K, Lucas JE, Thompson JW, Dubois LG, Tillmann HL, Thompson AJ, Uzarski D, Califf RM, Moseley MA, Ginsburg GS, McHutchison JG, McCarthy JJ; for the MURDOCK Horizon 1 Study Team.  Hepatology.  2011 Mar 4., PMCID: PMC3130042.


Microproteomics: quantitative proteomic profiling of small numbers of laser-captured cells.  Roulahc PL, Ward JM, Thompson JW, Soderblom EJ, Silva M, Moseley MA 3rd, Jarvis ED.  Cold Spring Harb Protoc.  2011 Feb 1, PMCID not available.  

2009-2010

Proteomic Profiling of  a Layered Tissue Reveals Unique Glycolytic Specializations of Photoreceptor Cells.  Reidel B, Thompson JW, Farsiu S, Moseley MA, Skiba NP, Arshavsky VY.  Mol Cell Proteomics.  2010 Dec 20, PMCID: PMC3047149.


Site-specifid analysis of protein S-acylation by resin-assisted capture (Acyl-RAC).  Forrester MT, Hess DT, Thompson JW, Hultman RC, Moseley MA, Stamler JS, Casey PJ.  J Lipid Res.  2010 Epub Nov 2, PMCID: PMC3023561.


Identification of s-nitrosylated targets of thioredoxin using a quantitative proteomic approach.  Benhar M, Thompson JW, Moseley MA, Stamler JS.  Biochemistry.  2010 Aug 17; 49(30): 6963-9, PMCID: PMC3008576.


Survival defects of Cryptococcus neorformans mutants in human cerebrospinal fluid resluts in attenuated virulence in an experimental mode of meningitis.  Lee A, Toffaletti DL, Tenor J, Soderblom EJ, Thompson JW, Moseley MA, Price M, Perfect JR.  Infect Immun.  2010 Epub Aug 9, PMCID: PMC2950369.


Kinetic characterization of Salmonella FliK-FlhB interactions demonstrates complexity of the Type III secretion substrate-specificity switch.  Morris DP, Roush ED, Thompson JW, Moseley MA, Murphy JW, McMurry JL.  Biochemistry.  2010 Aug 3; 49(30): 6386-93, PMCID: PMC2912450.


Mass spectrometry -based thermal shift assay for protein-ligand binding analysis.  West GM, Thompson JW, Soderblom EJ, Dubois LG, Dearmond PD, Moseley MA, Fitzgerald MC.  Anal Chem.  2010 Jul 1; 82(13): 5573-81, PMCID: PMC3085011.


Resistance to ErbB2 tyrosine kinase inhibitors in breast cancer is mediated by calcium-dependent activation of ReIA.  Xia W, Bacus S, Husain I, Liu L, Zhao S, Liu Z, Moseley MA 3rd, Thompson JW, Chen FL, Koch KM, Spector NL.  Mol Cancer Ther.  2010 Feb; 9(2): 292-9, PMCID: PMC3230295.


Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.  Andersen JL, Johnson CE, Freel CD, Parrish AB, Day JL, Buchakjian MR, Nutt LK, Thompson JW, Moseley MA, Kornbluth S.  EMBO J.  2009 Oct 21; 28(20): 3216-27, PMCID: PMC2771089.


Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture.  Forrester MT, Thompson JW, Foster MW, Nogueira L, Moseley MA, Stamler JS.  Nat Biotechnol.  2009 Jun; 27(6): 557-9, PMCID: PMC2891235.

Publications with Core Facility Contribution

High-Resolution Expression Map of the Arabidopsis Root Reveals Alternative Splicing and lincRNA Regulation. Li S, Yamada M, Han X, Ohler U, Benfey PN. Dev Cell 2016 Nov 21; 39(4); 508-522. PMID 27840108.


MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes.  Sachdeva M, Mito JK, Lee CL, Zhang M, Li Z, Dodd RD, Cason D, Luo L, Ma Y, Van Mater D, Gladdy R, Lev DC, Cardona DM, Kirsch DG.  J Clin Invest.  2014 Sep 2.  PMID: 25180607.


The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling.  Chen YS, Bastidas RJ, Saka HA, Carpenter VK, Richards KL, Plano GV, Valdivia RH.  PLoS Pathog.  2014 Feb 20; 10(2): e1003954.  doi: 10.1371/journal.ppat.  1003954.  eCollection 2014.


Mitotic Phosphorylation of Eukaryotic Initiation Factor 4G1 (elF4G1) at Sert1232 by Cdk1: Cyclin B Inhibits elF4A Helicase Complex Binding with RNA.  Dobrikov MI, Shveygert M, Brown MC, Gromeier M.  Mol Cell Biol.  2014 Feb;34(3): 439-51. doi: 10. 1128/MCB.01046-13.  Epub 2013 Nov 18.


The Ubiquitin Ligase CHIP Prevents SirT6 Degradation through Noncanonical Ubiquitination.  Ronnebaum SM, Wu Y, McDonough H, Patterson C.  Mol.  Cell Biol.  2013 Nov; 33(22):  4461-72, PMCID: PMC3838192.


Further Characterization of the Target of a Potential Aptamer Biomarker for Pancreatic Cancer: Cyclophilin B and Its Posttranslational Modifications.  Ray P, Sullenger BA, White RR.  Nucleic Acid Ther.  2013 Oct 23, PMCID: PMC3868381.


Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration.  Wang J, Karra R, Dickson AL, Poss KD.  Dev Biol.  2013 Oct 15;382(2): 427-35.  doi: 10.1016/j.ydbio.2013.08.012.  Epub 2013 Aug 26, PMCID: PMC3852765.


Cytoprotective effect of recombinant human erythropoietin produced in transgenic tobacco plants.  Kittur FS, Bah M, Archer-Hartmann S, Hung CY, Azadi P, Ishihara M, Sane DC, Xie J.  PLoS One.  2013 Oct 4;8(10):e76468.  doi: 10.1371/journal.pone0076468.  eCollection 2013.


Cell cycle regulated phosphorylation of the telomere-associated protein TIN2.  Yang S, Counter CM.  PLoS One.  2013 Aug 16;8(8):e71697, PMCID: 3745427.


A Truncated Progesterone Receptor (PR-M) Localizes to the Mitochondrion and Controls Cellular Respiration.  Dai Q, Shah AA, Garde RV, Yonish BA, Zhang L, Medvitz NA, Miller SE, Hansen EL, Dunn CN, Price TM.  Mol Endocrinol.  2013 May;27(5): 741-53, PMCID: PMC3634113.


Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.  Evsyukova I, Bradrick SS, Gregory SG, Garia-Blanco MA.  RNA.  2013 Jan;19(1):103- 15.  doi: 10.1261/rna.035410.112.  Epub 2012 Nov 14, PMCID: PMC3527722.


MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.  Han SO, Xiao K, Kim J, Wu JH, Wisler JW, Nakamura N, Freedman NJ, Shenoy SK.  J Cell Biol.  2012 Nov 26;199(5):817-30.  doi: 10.1083/jcb.201208192.  Epub 2012 Nov 19, PMCID: PMC3514787.


Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcelluar sites within cells.  Uezu A, Okada H, Murakoshi H, Del Vescovo CD, Yasuda R, Diviani D, Soderling SH.  Proc Natl Acad Sci USA.  2012 Oct 1, PMCID: PMC3491470.


Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker.  Ray P, Rialon-Guevara KL, Veras E, Sullenger BA, White RR.  J Clin Invest.  2012 Apr 9 (Epub ahead of print), PMCID: PMC3336995.


Protein modification by deamidation indicates variations in joint extracellular matrix turnover.  Catterall JB, Hsueh MF, Stabler TV, McCudden CR, Bolognesi M, Zura R, Jordan JM, Renner JB, Feng S, Kraus VB.  J Biol Chem.  2012 Feb 10;287(7): 4640-51, PMCID: PMC3281605.


Identification of potential prognostic biomarkers in patients with untreated, advanced pancreatic cancer from a phase 3 trial (Cancer and Leukemia Group B 80303).  Roberts AS, Campa MJ, Gottlin EB, Jiang C, Owzar K, Kindler HL, Venook AP, Goldberg RM, O'Reilly EM, Patz EF Jr.  Cancer.  2012 Jan 15;118(2): 571-8, PMCID: PMC3184330.


Phosphorylation of eukaryotic translation initiation factor 4G1 (elF4G1) by protein kinase C{alpha} regulates elF4G1 binding to Mnk1.  Dobrikov M, Dobrikova E, Shveygert M, Gromeier M.  Mol Cell Biol.  2011 Jul; 31(14): 2947-50.  Epub 2011 May 16, PMCID:  PMC3133411.


Phosphorylation of G protein-coupled receptor kinase 1 (GRK1) is regulated by light but independent of phototransduction in rod photoreceptors.  Osawa S, Jo R, Xiong Y, Reidel B, Tserentsoodol N, Arshavsky VY, luvone PM, Weiss ER.  J Biol Chem  2011 Jun 10;286(23): 20923-9.  Epub 2011 Apr 19, PMCID:  PMC3121460.


In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation.  Gao W, Liu W, Christensen T, Zalutsky MR, Chilkoti A.  Proc Natl Acad Sci USA.  2010 Sep 1, PMCID: PMC2944699.


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