nanoAcquity UPLC

Ultrahigh Pressure Nanoscale Capillary

LC Ultra-performance Nanoscale Liquid Chromatography - nanoAcquity UPLC

Four NanoAcquity systems and two Multidimensional NanoAcquity systems are available in our lab.

The nanoACQUITY UltraPerformance LC® (UPLC®) System is designed for nano-scale, capillary and narrow-bore separations to attain the highest chromatographic resolution, sensitivity and reproducibility.nanoACQUITY UPLC System

Direct nano-flow offers significant improvements over conventional nano-flow separations technologies. You'll see improved peak capacity and shape and increase the number of components detected per separation.

The system's 10,000 psi operating pressure capability allows for superior high-peak capacity separations by operating longer columns packed with sub-2 micron particles. It is optimized for high-resolution identification and 2D-LC separations at precise nano-flow rates:

Nano-flow Rates From:On nanoACQUITY UPLC Columns*:
200 nL/min to 100 uL/min
  • 70 um to 1 mm internal diameter
without flow splitting
  • 100 mm to 250 mm long
 Available with BEH, Atlantis, and
 Symmetry chemistries

The nanoACQUITY UPLC System provides solutions for biomarker discovery and proteomics applications for protein identification and characterization.

nanoACQUITY UPLC System Features:

  • Customize your throughput and condition requirements with comprehensive system components including the nanoACQUITY® Heating and Trapping Module, the Sample Manager, the Binary Solvent Manager, and the Auxiliary Solvent Manager (optional).
  • Monitor system performance with enhanced on-board diagnostics.
  • Extend high-sensitivity nano-scale MS analyses:
    • Quattro PremierTM XE tandem quadrupole mass spectrometer for routine quantification
    • SYNAPTTM HDMSTM System for cutting edge applications
    • IdentityE High Definition Proteomics System for protein identification
  • Predictive system support with Connections INSIGHT®  remote intelligent services.
  • Instrument control and data processing with MassLynxTM Software.
  • Easily compatible with third-party MS solutions.
  • FlexCart lets you move nanoACQUITY UPLC system from one MS to another.
  • Stand-alone nanoACQUITY UPLC console provides easy instrument control.