Gregory A. Wray, PhD
Publications
Haygood R, Fedrigo O, Hanson B, Yokoyama KD, Wray GA.
Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution.
Nat Genet. 2007 Aug 12; [Epub ahead of print]
PMID: 17694055 [PubMed - as supplied by publisher]
Wray GA.
The evolutionary significance of cis-regulatory mutations.
Nat Rev Genet. 2007 Mar;8(3):206-16. Review.
PMID: 17304246 [PubMed - indexed for MEDLINE]
Tishkoff SA, Reed FA, Ranciaro A, Voight BF, Babbitt CC, Silverman JS, Powell K, Mortensen HM, Hirbo JB, Osman M, Ibrahim M, Omar SA, Lema G, Nyambo TB, Ghori J, Bumpstead S, Pritchard JK, Wray GA, Deloukas P.
Convergent adaptation of human lactase persistence in Africa and Europe.
Nat Genet. 2007 Jan;39(1):31-40. Epub 2006 Dec 10.
PMID: 17159977 [PubMed - indexed for MEDLINE]
Loisel DA, Rockman MV, Wray GA, Altmann J, Alberts SC.
Ancient polymorphism and functional variation in the primate MHC-DQA1 5' cis-regulatory region.
Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16331-6. Epub 2006 Oct 19.
PMID: 17053068 [PubMed - indexed for MEDLINE]
Romano LA, Wray GA.
Endo16 is required for gastrulation in the sea urchin Lytechinus variegatus.
Dev Growth Differ. 2006 Oct;48(8):487-97.
PMID: 17026713 [PubMed - indexed for MEDLINE]
Wray GA.
Evolution: spot on (and off).
Nature. 2006 Apr 20;440(7087):1001-2. No abstract available.
PMID: 16625184 [PubMed - indexed for MEDLINE]
Rudd MK, Wray GA, Willard HF.
The evolutionary dynamics of alpha-satellite.
Genome Res. 2006 Jan;16(1):88-96. Epub 2005 Dec 12.
PMID: 16344556 [PubMed - indexed for MEDLINE]
Mooi R, David B, Wray GA.
Arrays in rays: terminal addition in echinoderms and its correlation with gene expression.
Evol Dev. 2005 Nov-Dec;7(6):542-55. Review.
PMID: 16336408 [PubMed - indexed for MEDLINE]
Rockman MV, Hahn MW, Soranzo N, Zimprich F, Goldstein DB, Wray GA.
Ancient and recent positive selection transformed opioid cis-regulation in humans.
PLoS Biol. 2005 Dec;3(12):e387.
PMID: 16274263 [PubMed - indexed for MEDLINE]
Balhoff JP, Wray GA.
Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites.
Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8591-6. Epub 2005 Jun 3.
PMID: 15937122 [PubMed - indexed for MEDLINE]
Wray GA, Kitazawa C, Miner B.
Culture of echinoderm larvae through metamorphosis.
Methods Cell Biol. 2004;74:75-86. Review. No abstract available.
PMID: 15575603 [PubMed - indexed for MEDLINE]
Ettensohn CA, Wessel GM, Wray GA.
The invertebrate deuterostomes: an introduction to their phylogeny, reproduction, development, and genomics.
Methods Cell Biol. 2004;74:1-13. Review. No abstract available.
PMID: 15575600 [PubMed - indexed for MEDLINE]
Rockman MV, Hahn MW, Soranzo N, Loisel DA, Goldstein DB, Wray GA.
Positive selection on MMP3 regulation has shaped heart disease risk.
Curr Biol. 2004 Sep 7;14(17):1531-9.
PMID: 15341739 [PubMed - indexed for MEDLINE]
Hahn MW, Rockman MV, Soranzo N, Goldstein DB, Wray GA.
Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans.
Genetics. 2004 Jun;167(2):867-77.
PMID: 15238535 [PubMed - indexed for MEDLINE]
Bely AE, Wray GA.
Molecular phylogeny of naidid worms (Annelida: Clitellata) based on cytochrome oxidase I.
Mol Phylogenet Evol. 2004 Jan;30(1):50-63.
PMID: 15022757 [PubMed - indexed for MEDLINE]
Wray GA.
Transcriptional regulation and the evolution of development.
Int J Dev Biol. 2003;47(7-8):675-84. Review.
PMID: 14756343 [PubMed - indexed for MEDLINE
Rockman MV, Hahn MW, Soranzo N, Goldstein DB, Wray GA.
Positive selection on a human-specific transcription factor binding site regulating IL4 expression.
Curr Biol. 2003 Dec 2;13(23):2118-23.
PMID: 14654003 [PubMed - indexed for MEDLINE]
Romano LA, Wray GA.
Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation.
Development. 2003 Sep;130(17):4187-99.
PMID: 12874137 [PubMed - indexed for MEDLINE]
Knott KE, Balser EJ, Jaeckle WB, Wray GA.
Identification of asteroid genera with species capable of larval cloning.
Biol Bull. 2003 Jun;204(3):246-55.
PMID: 12807702 [PubMed - indexed for MEDLINE]
Wray GA, Hahn MW, Abouheif E, Balhoff JP, Pizer M, Rockman MV, Romano LA.
The evolution of transcriptional regulation in eukaryotes.
Mol Biol Evol. 2003 Sep;20(9):1377-419. Epub 2003 May 30. Review.
PMID: 12777501 [PubMed - indexed for MEDLINE]
Hahn MW, Stajich JE, Wray GA.
The effects of selection against spurious transcription factor binding sites.
Mol Biol Evol. 2003 Jun;20(6):901-6. Epub 2003 Apr 25.
PMID: 12716998 [PubMed - indexed for MEDLINE]
Contact Information
Gregory A. Wray
Phone: 919-684-6696
4104 French Family Science Center.
gwray@duke.edu