David B. Goldstein, PhD
Research Interests
The Goldstein laboratory studies how genetic variation influences response to drug treatment. The lab currently focuses on the treatment of common neurological and cardiovascular conditions, as well as well as more general questions such how genetic variation contributes to problems caused by drug-drug interactions.
A key priority of our work is to move beyond simple correlations between genetic variation and disease, and to ground the study of genetic variation squarely within human biology. For this reason we focus considerable attention on understanding the functional effects of common genetic variation, both in pathological and non-pathological settings. For instance we investigate how genetic variation can predispose to epilepsy, how it can affect response to epilepsy treatment, and how it contributes to inter-individual variation in characteristics of epileptogenic brain regions and related functions such as memory and cognition.
Contact Information
David B. Goldstein
IGSP Center for Human Genome Variation
IGSP, Duke University
450 Research Drive, Box 91009
LSRC B Wing, Room 330
Durham, NC 27708
(P) 919-684-0896
Angelique Cherry
Assistant to Dr. Goldstein
Phone: 919-684-0896
330 LSRC B Wing
angelique.cherry@duke.edu