Sandeep Dave, MD, MS

Research Interests

Leukemias and lymphomas are malignancies that arise from immune cells. The majority of these malignancies arise from B cells, a type of immune cell. Leukemias and lymphomas derived from B cells affect over 100,000 Americans every year. The majority of those patients will succumb to their disease. Dr. Dave's research is focused on the application of high-throughput technologies including microarrays and massively parallel sequencing to improve the diagnosis and treatment of leukemias and lymphomas.

Active efforts in the laboratory and clinic include:

  1. Integrating genomic technologies with clinical trials to define molecular subgroups of patients who are most likely to respond to therapy.
  2. Exploring the role of microRNA in the differentiation of immune cells and their role in leukemias and lymphomas.
  3. Application of high throughput sequencing to identify means of gene regulation in normal and malignant cells.
  4. Exploiting high throughput genomic and proteomic technologies to develop new prognostic and diagnostic markers in leukemias and lymphomas.

 

 

 

Contact Information

Sandeep Dave
Phone: 919-681-1922
FCIEMAS 2177C
Box DUMC 3382
sandeep.dave@duke.edu

Details