Greg Crawford, PhD
Publications
Boyle AP, Davis S, Shulha HP, Meltzer P, Margulies EH, Weng Z, Furey TS, Crawford GE.
High-resolution mapping and characterization of open chromatin across the genome.
Cell. 2008 Jan 25;132(2):311-22.
PMID: 18243105 [PubMed - in process]
Eguchi J, Yan QW, Schones DE, Kamal M, Hsu CH, Zhang MQ, Crawford GE, Rosen ED.
Interferon regulatory factors are transcriptional regulators of adipogenesis.
Cell Metab. 2008 Jan;7(1):86-94.
PMID: 18177728 [PubMed - in process]
Xi H, Shulha HP, Lin JM, Vales TR, Fu Y, Bodine DM, McKay RDG,
Chenoweth JG, Tesar PJ, Furey TS, Ren B, Weng Z, and Crawford GE
Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome.
PLoS Genet. 2007 Aug;3(8):e136. Epub 2007 Jul 2.
PMID: 17708682 [PubMed - indexed for MEDLINE]
The ENCODE Project Consortium
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Nature. 2007 Jun 14;447(7146):799-816.
PMID: 17571346 [PubMed - indexed for MEDLINE].
Heintzman ND, Stuart RK, Hon G, Fu Y, Ching CW, Hawkins D, Barrera LO, Calcar SV, Qu C, Ching KA, Wang W, Weng Z, Green RD, Crawford GE, and Ren B
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome.
Nat Genet. 2007 Mar;39(3):311-8. Epub 2007 Feb 4.
PMID: 17277777 [PubMed - indexed for MEDLINE]
Nagel S, Scherr M, Kel A, Hornischer K, Crawford GE, Kaufmann M,
Meyer C, Drexler HG, and MacLeod RA
Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.
Cancer Res. 2007 Feb 15;67(4):1461-71.
PMID: 17308084 [PubMed - indexed for MEDLINE]
Crawford GE, Davis S, Scacheri PC, Renaud G, Green R, Meltzer PS,
Wolfsberg TG, Collins FS
DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays.
Nat Methods. 2006 Jul;3(7):503-9.
PMID: 16791207 [PubMed - indexed for MEDLINE]
Scacheri PC, Crawford GE, Davis S
Statistics for ChIP-chip and DNase hypersensitivity experiments on NimbleGen arrays.
Methods Enzymol. 2006;411:270-82. Review.
PMID: 16939795 [PubMed - indexed for MEDLINE]
Bernat JA, Crawford GE, Ogurtsov A, Collins FS, Ginsburg D,
Kondrashov AS
Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs.
Hum Mol Genet. 2006 Jul 1;15(13):2098-105. Epub 2006 May 24.
PMID: 16723375 [PubMed - indexed for MEDLINE]
Lewinski MK, Yamashita M, Emerman M, Ciuffi A, Marshall H, Crawford G, Collins FS, Shinn P, Leipzig J, Hannenhalli S, Berry CC, Ecker JR, Bushman FD
Retroviral DNA integration: viral and cellular determinants of target-site selection.
PLoS Pathog. 2006 Jun;2(6):e60. Epub 2006 Jun 23.
PMID: 16789841 [PubMed - indexed for MEDLINE]
Crawford GE, Holt I, Whittle J, Webb BD, Tai D, Davis S, Margulies
EH, Chen Y, Bernat J, Ginsburg D, Zhou D, Luo S, Vasicek TJ, Daly MJ,
Wolfsberg TG, and Collins FS
Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS).
Genome Res. 2006 Jan;16(1):123-31. Epub 2005 Dec 12.
PMID: 16344561 [PubMed - indexed for MEDLINE]
Yan J, Xu L, Crawford GE, and Burgess S
The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure.
Mol Cell Biol. 2006 Jan;26(1):155-68.
PMID: 16354687 [PubMed - indexed for MEDLINE]
The ENCODE Consortium
The ENCODE (ENCyclopedia Of DNA Elements) Project.
Science. 2004 Oct 22;306(5696):636-40.
PMID: 15499007 [PubMed - indexed for MEDLINE]
Crawford GE, Holt IE, Mullikin JC, Tai D, NIH Intramural
Sequencing Center, Green ED, Wolfsberg TG, and Collins FS
Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites.
Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):992-7. Epub 2004 Jan 19.
PMID: 14732688 [PubMed - indexed for MEDLINE]
Crawford GE, Partridge TA, and Chamberlain JS
Suppression of revertant fibers in mdx mice by expression of a functional dystrophin.
Hum Mol Genet. 2001 Nov 15;10(24):2745-50.
PMID: 11734539 [PubMed - indexed for MEDLINE]
Crawford GE, Faulkner JA, Crosbie RH, Campbell KP, Froehner SC,
and Chamberlain JS
Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain.
J Cell Biol. 2000 Sep 18;150(6):1399-410.
PMID: 10995444 [PubMed - indexed for MEDLINE]
Lumeng C, Phelps S, Crawford GE, Walden PD, Barald K, and
Chamberlain JS
Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.
Nat Neurosci. 1999 Jul;2(7):611-7.
PMID: 10404183 [PubMed - indexed for MEDLINE]
Contact Information
Greg Crawford
Phone: 919-684-8196
Room 2363B,
CIEMAS
greg.crawford@duke.edu