Avshalom Caspi, PhD
Recent Publications
Moffitt, T. E., Caspi, A., & Rutter, M. (2005). A research strategy for investigating interactions between measured genes and measured environments. Archives of General Psychiatry, 62, 473-481.
Caspi, A. Moffitt, T. E., Cannon, M., McClay, J., Murray, R., Harrington, HL, Taylor, A., Arseneault, L., Williams, B., Braithwaite, A., Poulton, R., Craig, I. W. (2005). Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the COMT gene: Longitudinal evidence of a gene X environment interaction. Biological Psychiatry, 57, 1117-1127.
Rutter, M., Moffitt, T. E., & Caspi, A. (2006). Gene-environment interplay and psychopathology: Multiple varieties but real effects.
Journal of Child Psychology and Psychiatry, 47, 226-261.
Moffitt, T. E., Caspi, A., & Rutter, M. (2006). Measured gene-environment interactions in psychopathology: Concepts, research strategies, and implications for research, intervention, and public understanding of genetics. Perspectives on Psychological Science, 1, 5-27.
Caspi, A., & Moffitt, T. E. (2006). Gene-environment interactions in
psychiatry: Joining forces with neuroscience? Nature Reviews Neuroscience, 7, 583-590.
Mill, J., Caspi, A., Williams, B. S., Craig, I., Taylor, A., Polo-Tomas, M., Berridge, C., Poulton, R., & Moffitt, T. E. (2006).
Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with Attention-Deficit/Hyperactivity Disorder. Archives of General Psychiatry, 63, 462-469.
Kim-Cohen, J., Caspi, A., Williams, B., Taylor, A., Newcombe, R., Craig, I. W., & Moffitt, T. E. (2006). MAOA, maltreatment and gene-environment interaction predicting children's mental health: New evidence and a meta-analysis. Molecular Psychiatry, 11, 903-913.
Mill, J., Dempster, E., Caspi, A., Williams, B., Moffitt, T. E., & Craig, I. (2006). Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the Catechol-O-Methyltransferase (COMT) gene. American Journal of Medical Genetics, 141B, 319-433.
Koenen, K.C., Moffitt, T.E., Caspi, A., & Rijsdijk, F., & Taylor, A.
(2006). Genetic influences on the overlap between low IQ and antisocial behavior in young children. Journal of Abnormal Psychology, 115, 787-797.
Bricker, J., Stallings, M. Corley, R., Wadsworth, S., Bryan, A., Timberlake, D., Hewitt, J., Caspi, A., Hofer, S., Rhea, S.A., & DeFries, J. C. (2006). Genetic and environmental influences on age at sexual initiation in the Colorado Adoption Project. Behavior Genetics, 36, 820-832.
Caspi, A., Williams, B., Kim-Cohen, J., Craig, I. W., Milne, B.J., Poulton, R., Schalkwyk, L. C., Taylor, A., Werts, H., & Moffitt, T. E.
(2007). Nature, nurture, and the IQ: Genetic variation in fatty acid metabolism moderates the association between breastfeeding and children's cognitive development. Proceedings of the National Academy of Sciences (PNAS), 104, 18860-18865.
Caspi, A., Langley, K. Milne, B., Moffitt, T. E., O’Donovan, M., Owen, M. J., Polo Tomas, M., Poulton, R., Rutter, M., Taylor, A., Williams, B., & Thapar, A. (2008). A replicated molecular-genetic basis for subtyping antisocial behavior in ADHD. Archives of General Psychiatry, 65, 203-210.
Arseneault, L., Milne, B., Taylor, A., Adams, F., Delgado, K., Caspi, A., & Moffitt, T.E. (2008). Evidence that bullying victimization is an environmentally-mediated contributing factor to children's internalizing
problems: A study of twins discordant for victimization. Archives of Pediatrics and Adolescent Medicine, 162, 145-150.
Milne, B. J., Caspi, A., Crump, R., Poulton, R., Rutter, M.R, Sears, M., Taylor, A., & Moffitt, T.E. (In press). How should we construct family history scores? A comparison of alternative approaches from the Dunedin Family Health History Study. Psychological Medicine.
Milne, B. J., Caspi, A., Crump, R., Poulton, R., Rutter, M., Sears, M.
R., & Moffitt, T. E. (In press). The validity of the Family History Screen for assessing family history of mental disorders. American Journal of Medical Genetics.
Baker, T., Moffitt, T. E., & Caspi, A. (In press). Phenotypes and endophenotypes. Foundations for Genetic Studies of Nicotine Use and Dependence. NCI Tobacco Control Monograph (Monograph No. 20). Bethesda, MD: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute.
Contact Information
Avshalom Caspi
Phone: 919-684-5835
avshalom.caspi@duke.edu
Physical Address:
Grey House
2020 W. Main Street, Suite 201
Postal Address:
Box 104410
Durham, NC 27708



