Fall 2007

BIOLOGY 49S -Biotech & the New Genetics
Instructor: Ron Grunwald; T-Th 1:15p-2:30p, Th 2:50p-4:05p
Topics vary each semester offered.

BIOLOGY 118 -Genetics and Molecular Biology
Instructor: Eric Spann, Amy Bejsovec; (various times)
Explores flow of information from gene to phenotype. Social implications of modern genetic analysis and the genomic revolution. Topics include: organization and stability of genomes from bacteria to higher vertebrates (humans), conversion of the genetic code into a functioning organism, classical transmission (Mendelian) genetics and its relevance to human hereditary disorders, content of the genome and social implications of genetic knowledge including issues of genetic privacy, eugenics, genetically modified organism, and cloning. Prerequisite: Biology 25L or equivalent; Chemistry 22L or equivalent.

BIOLOGY 195S - Genomes, Biology, Medicine
Instructor: Hunt Willard; M-W 2:50p-4:05p

BIOLOGY 280S - Genetic Engineer/Biotech
Instructor: Tai-Ping Sun; T 2:50p-5:20p
Applications of recombinant DNA in medicine and in agriculture. Topics include diagnosis of genetic diseases, gene therapy, drugs for AIDS and cancer, DNA fingerprinting, cloning of mammals, phytoremediation, crop improvement, and pharmaceutical protein production in transgenic plants and animals. Social and environmental impacts of biotechnology. Prerequisites: Biology 118 and 119 or consent of instructor.

BIOLOGY 283/CELLBIO 283 - Developmental Genetics
Instructor: John Klingensmith; T-Th 10:05a-11:20a
Half-semester mini-course targeted to first year graduate students in the Biological Sciences. Taught sequentially in the Fall semester with Biology 282. Focuses on genetic approaches to solve mechanistic problems of development. Emphasis is on model organisms, mainly Drosophilia, C. elegans, mouse and zebrafish, where genomics, mutations, gene modifiers, epistasis analysis, gene knockouts, and transgenesis, plus many other genetic approaches have yielded important insights into the differentiation of cell and the development of complex organisms. Cross-listed with Biology 283.

BME 265 - Model & Eng Gene Circuits
Instructor: Lingchong You; T-Th 10:05a-11:20a
Advanced subjects related to programs within biomedical engineering tailored to fit the requirements of a small group. Consent of instructor required.

CBB 220 - Genome Tools and Technologies
Instructor: Fred Dietrich; T-Th 10:05a-11:20a
This course introduces the laboratory and computational methodologies for genetic and protein sequencing, mapping and expression measurement.

CBB 222/BME258L - Genome Science Technology Lab
Instructor: Jingdong Tian; T-Th 2:50p-4:05p
Hands-on experience on using and developing advanced technology platforms for genomics and proteomics research. Experiments may include nucleic acid amplification and quantification, lab-on-chip, bimolecular separation and detection, DNA sequencing, SNP genotyping, microarrays, and synthetic biology techniques. Laboratory exercises and designing projects are combined with lectures and literature reviews. Instructor and prior knowledge in molecular biology and biochemistry is required.

COMPSCI 4G - Intro Programming with Genomics
Instructor: Owen Astrachan; T-Th 10:05a-11:20a
Problem-solving techniques using a computer, top-down decomposition and object-oriented solution methodologies, introduction to programming in the Java language, introduction to toolkits for programming genomics example such as BioJava and BioPerl, simple CGI programming, introduction to dynamic programming, web protocols. Contributions of computational techniques to the human genome project and genomics. Technical and social implications of genomics and genome studies made possible by advances in algorithms, computational methods, and computational models. (Not open to students who have taken Computer Science 6 or 6X.)

ENGLISH 173/ISIS 120/LIT 132 - New Media, Lit, & Genes
Instructor: Rob Mitchell; T-Th 1:15p-2:30p

PUBPOL 81FCS/HISTORY 89FCS - Social & Pol Hist of Genomics
Instructor: Bob Cook Deegan; T 4:25p-6:55p
Introductory and basic topics in public policy. Topics vary each semester. Does not count for public policy studies major. Open only to students in the Focus program