Kris Wood is an Assistant Professor in Pharmacology and Cancer Biology. He received his Ph.D. in Chemical Engineering from the Massachusetts Institute of Technology working with Paula Hammond and Robert Langer. Kris completed postdoctoral training with David Sabatini at the Whitehead Institute for Biomedical Research and the Broad Institute of Harvard and MIT, where he was supported by an NIH Kirschstein National Research Service Award and a Misrock Fund Postdoctoral Fellowship. He joined the Duke faculty in 2012.
The Wood laboratory develops state-of-the-art tools for large-scale, efficient, and information-rich mammalian functional genomics experiments. Further, we use these tools to address problems in basic and translational cancer biology, many of which center on the design of targeted therapeutic strategies to robustly manipulate oncogenic signaling networks. Examples of current projects in our lab include: (1) the application of a new miniaturized screening platform to profile drug responses in human patient-derived tumor cells in real-time; (2) the development of tools to systematically elucidate the signaling pathways controlling anticancer drug responses; (3) the systematic credentialing of mutations uncovered through cancer genome sequencing projects; and (4) the use of new high-throughput experimental and computational methods to discover potent, selective anticancer drug combinations.
Learn more about Dr. Wood's research in GenomeLIFE
Wood KC, Konieczkowski DJ, Johannessen CM, Boehm JS, Tamayo P, Botvinnik OB, Mesirov JP, Hahn WC, Root DE, Garraway LA, Sabatini DM, Sci Signal. 2012;5(224):rs4. Abstract
Wood KC, Sabatini DM, Cell Stem Cell. 2009 Sep 4;5(3):232-4. Abstract
Wood KC, Zacharia NS, Schmidt DJ, Wrightman SN, Andaya BJ, Hammond PT, Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2280-5. Abstract
Wood KC, Azarin SM, Arap W, Pasqualini R, Langer R, Hammond PT, Bioconjug Chem. 2008 Feb;19(2):403-5. Abstract
Wood KC, Chuang HF, Batten RD, Lynn DM, Hammond PT, Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10207-12. Abstract
© 2004-2013, Duke Institute for Genome Sciences & Policy. Duke University | Duke Medicine | Interdisciplinary Studies at Duke