Directory of CBB Program Faculty by Research Areas
(Alphabetical list of faculty)
Systems Biology
Faculty in this inter-disciplinary area focus on the systematic study of complex interactions in biological systems, integrating and analyzing complex data from multiple experimental sources. Many are members of the IGSP’s Center for Systems Biology, which has as its central research theme the study of network dynamics across various time scales, including temporal changes in both network state and structure. Current focus is on a variety of biological systems including: budding yeast, sea urchins, plant roots, worms, and human cell lines.
- Pankaj Agarwal
- Ryan Baugh
- Phillip Benfey
- Nicholas Buchler
- Blanche Capel
- Herbert Edelsbrunner
- Steve Haase
- John Harer
- Alex Hartemink
- Edwin Iversen
- Erich Jarvis
- Paul Magwene
- Dave McClay
- Sayan Mukherjee
- Uwe Ohler
- Sridhar Raghavachari
- Amy Schmid
- Joshua Socolar
- Mike West
- Greg Wray
- Lingchong You
- Jun Zhu
Genome Analysis
Faculty in this area take advantage of the vast amount of data made available through the Human Genome Project and other large-scale sequencing efforts, applying computational approaches to understand and predict the function of DNA.
- Greg Crawford
- Fred Dietrich
- Terry Furey
- Alex Hartemink
- Katia Koelle
- David MacAlpine
- Sayan Mukherjee
- Mohamed Noor
- Uwe Ohler
- Mike West
- Huntington Willard
Structural Computational Biology
Faculty in this area use computational approaches to help resolve molecular structures of macromolecules and uncover their interactions. Many of these faculty are also part of Duke’s Structural Biology & Biophysics Program.
- Pankaj Agarwal
- David Beratan
- Patrick Charbonneau
- Bruce Donald
- Herbert Edelsbrunner
- Homme Hellinga
- Terrence Oas
- David Richardson
- Jane Richardson
- Scott Schmidler
- Jingdong Tian
- Weitao Yang
Medical Genomics
Faculty in this area apply large-scale genomic technologies (transcriptomics, proteomics, metabolomics, genome-wide association studies) to understand and predict human diseases and traits. Most of these faculty are affiliated with the Medical Center and include physician-scientists, statisticians and population geneticists.
- Cliburn Chan
- Jen-Tsan Ashley Chi
- Merlise Clyde
- Sandeep Dave
- Phillip Febbo
- David Goldstein
- Simon Gregory
- Elizabeth Hauser
- Edwin Iversen
- Joseph Lucas
- David MacAlpine
- Jeanette McCarthy
- Sayan Mukherjee
- Joseph Nevins
- Georgia Tomaras
- Mike West
Mathematical and Statistical Modeling of Biological Systems
A common theme in the work of many faculty in CBB is the use of Mathematical and Statistical Models to study biological questions. Areas of application are widespread and include immunology, physiology, metabolic and gene regulatory networks, ecology and population biology and evolutionary biology.
- Lindsay Cowell
- Herbert Edelsbrunner
- John Harer
- Garnett Kelsoe
- Thomas Kepler
- Katia Koelle
- Anita Layton
- Sayan Mukherjee
- Fred Nijhout
- Mike Reed
- Marcy Uyenoyama
Evolutionary Genomics
Faculty in this area use computational approaches to study how changes in the content and organization of genomes have contributed to the diversity of life on Earth, as well as the processes that have shaped these changes. Many are part of the IGSP’s Center for Evolutionary Genomics.



